Spark PLUS UV395™ anti-mouse CD107a (LAMP-1) Antibody, CD107a, 1D4B

Pricing & Availability

Clone: 1D4B (See other available formats)
Regulatory Status: RUO
Other Names: Lysosome-associated membrane glycoprotein 1, lysosomal membrane glycoprotein 1, CD107 antigen-like family member A, lysosome-associated membrane protein 1
Isotype: Rat IgG2a, κ
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1D4B_SparkPLUSUV395_CD107a_Antibody_1_061725 — Thioglycollate-elicited BALB/c mouse peritoneal macrophages were stained with anti-mouse CD107a (LAMP-1) (clone 1D4B) Spark PLUS UV395™ (filled histogram) or rat IgG2a, κ Spark PLUS UV395™ isotype control (open histogram).

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121647

25 µg

144€

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Description

CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.

Product Details

Technical Data Sheet (pdf)

Product Details

Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: This monoclonal antibody was raised against NIH/3T3 mouse embryonic fibroblast tissue culture cell membranes. It has been mapped to the N-terminus of LAMP-1.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography and conjugated with Spark PLUS UV395™ under optimal conditions.
Concentration: 0.2 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

* Spark PLUS UV395™ has a maximum excitation of 355 nm and a maximum emission of 385 nm.
Excitation Laser: Ultraviolet Laser (355 nm)
RRID: AB_3720510 (BioLegend Cat. No. 121647)

Antigen Details

Structure: LAMP-1 is a 406 amino acid protein with a molecular mass of 44 kD.
Gene ID: 16783 View all products for this Gene ID
UniProt: View information about CD107a on UniProt.org

Documentation

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Related Protocols

Cell Surface Flow Cytometry Staining Protocol

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Other Formats

View All CD107a Reagents Request Custom Conjugation

Description	Clone	Applications
PE/Dazzle™ 594 anti-mouse CD107a (LAMP-1)	1D4B	FC
Alexa Fluor® 594 anti-mouse CD107a (LAMP-1)	1D4B	IHC-F
PerCP/Cyanine5.5 anti-mouse CD107a (LAMP-1)	1D4B	FC
Alexa Fluor® 700 anti-mouse CD107a (LAMP-1)	1D4B	FC
Brilliant Violet 510™ anti-mouse CD107a (LAMP-1)	1D4B	FC
Brilliant Violet 711™ anti-mouse CD107a (LAMP-1)	1D4B	FC
APC/Fire™ 750 anti-mouse CD107a (LAMP-1)	1D4B	FC
TotalSeq™-A0905 anti-mouse CD107a (LAMP-1)	1D4B	PG
TotalSeq™-C0905 anti-mouse CD107a (LAMP-1)	1D4B	PG
TotalSeq™-B0905 anti-mouse CD107a (LAMP-1)	1D4B	PG
PE anti-mouse CD107a (LAMP-1)	1D4B	FC
Purified anti-mouse CD107a (LAMP-1)	1D4B	FC,WB,ICC,IP
FITC anti-mouse CD107a (LAMP-1)	1D4B	FC
Alexa Fluor® 488 anti-mouse CD107a (LAMP-1)	1D4B	FC
Alexa Fluor® 647 anti-mouse CD107a (LAMP-1)	1D4B	FC
Biotin anti-mouse CD107a (LAMP-1)	1D4B	FC
APC anti-mouse CD107a (LAMP-1)	1D4B	FC
APC/Cyanine7 anti-mouse CD107a (LAMP-1)	1D4B	FC
Brilliant Violet 421™ anti-mouse CD107a (LAMP-1)	1D4B	FC
PE/Cyanine7 anti-mouse CD107a (LAMP-1)	1D4B	FC
Brilliant Violet 785™ anti-mouse CD107a (LAMP-1)	1D4B	FC
Spark Red™ 718 anti-mouse CD107a (LAMP-1) (Flexi-Fluor™)	1D4B	FC
Brilliant Violet 605™ anti-mouse CD107a (LAMP-1)	1D4B	FC
Brilliant Violet 650™ anti-mouse CD107a (LAMP-1)	1D4B	FC
Spark Blue™ 550 anti-mouse CD107a (LAMP-1) (Flexi-Fluor™)	1D4B	FC
Spark Blue™ 574 anti-mouse CD107a (LAMP-1) (Flexi-Fluor™)	1D4B	FC
Spark PLUS UV395™ anti-mouse CD107a (LAMP-1) Antibody	1D4B	FC
Spark YG™ 581 anti-mouse CD107a (LAMP-1) (Flexi-Fluor™)	1D4B	FC
Spark NIR™ 685 anti-mouse CD107a (LAMP-1) (Flexi-Fluor™)	1D4B	FC
Spark YG™ 593 anti-mouse CD107a (LAMP-1) (Flexi-Fluor™)	1D4B	FC

Certificate of Analysis

Go To Top Version: 1 Revision Date: 06-17-2025

For Research Use Only. Not for diagnostic or therapeutic use.

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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