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PE/Cyanine7 anti-mouse/human CD11b Antibody

Pricing & Availability
Clone
M1/70 (See other available formats)
Regulatory Status
RUO
Other Names
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
Isotype
Rat IgG2b, κ
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Product Citations
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M1slash70_PECy7_042706
C57BL/6 mouse bone marrow cells were stained with CD11b (clone M1/70) PE/Cyanine7 (filled histogram) or rat IgG2b, κ PE/Cyanine7 isotype control (open histogram) (gated on total cells).
  • M1slash70_PECy7_042706
    C57BL/6 mouse bone marrow cells were stained with CD11b (clone M1/70) PE/Cyanine7 (filled histogram) or rat IgG2b, κ PE/Cyanine7 isotype control (open histogram) (gated on total cells).
Compare all formats See PE/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
101215 25 µg 70€
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101216 100 µg 169€
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Description

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human, Cynomolgus, Rhesus
Reported Reactivity
Chimpanzee, Baboon, Rabbit
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
C57BL/10 splenocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F).

Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1,4, in vitro blocking3,9,12, depletion2,8, immunofluorescence microscopy6,7,10, immunohistochemistry of acetone-fixed frozen sections5,11-13, and spatial biology (IBEX)35,36. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).

Application References
  1. Springer T, et al. 1978. Eur. J. Immunol. 8:539. (IP)
  2. Ault K and Springer T. 1981. J. Immunol. 126:359. (Deplete)
  3. Springer TA, et al. 1982. Immunol. Rev. 68:171. (Block)
  4. Ho MK and Springer TA. 1983. J. Biol. Chem. 258:2766. (IP)
  5. Flotte TJ, et al. 1983. Am. J. Pathol. 111:112. (IHC)
  6. Noel GJ, et al. 1990. J. Clin. Invest. 85:208. (IF)
  7. Allen LA and Aderem A. 1996. J. Exp. Med. 184:627 (IF)
  8. D'Amico A and Wu L. 2003. J. Exp. Med. 198:293. (Deplete)
  9. Brickson SJ, et al. 2003. Appl Physiol. 95:969. (Block)
  10. Clatworthy MR and Smith KG. 2004. J. Exp. Med. 199:717. (IF)
  11. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  12. Zhang Y, et al. 2002. J. Immunol. 168:3088. (IHC)
  13. Iwasaki A and Kelsall BL. 2001. J. Immunol. 166:4884 (IHC, FC)
  14. Tailleux L. 2003. J. Exp. Med. 197:121. (Block, FC)
  15. Olver S, et al. 2006. Cancer Research 66:571. (FC)
  16. Tan SL, et al. 2006. J. Immunol. 176:2872. (FC) PubMed
  17. Ponomarev ED, et al. 2006. J. Immunol. 176:1402. (FC)
  18. Dzhagalov I, et al. 2007. Blood 109:1620. (FC)
  19. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  20. Rasmussen JW, et al. 2006. Infect. Immun.74:6590. PubMed
  21. Napimoga MH, et al. 2008. J. Immunol. 180:609. PubMed
  22. Elqaraz-Carmon V, et al. 2008. J. Lipid. Res. 49:1894. PubMed
  23. Kim DD, et al. 2008. Blood 112:1109. PubMed
  24. Guo Y, et al. 2008. Blood 112:480. PubMed
  25. Norian LA, et al. 2009. Cancer Res. 69:3086. (FC) PubMed
  26. Baumgartner CK, et al. 2010. J. Immunol. 184:573. PubMed
  27. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  28. Whiteland J, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
  29. Weber GF, et al. 2014. J Exp Med. 211:1243. PubMed
  30. Ashok A, et al. 2015. Toxicol Sci. 143:64. PubMed
  31. Price PJ, et al. 2015. J Immunol. 194:1164. PubMed
  32. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  33. Ferreira R, et al. 2016. J Infect Dis. 213: 669 - 673. PubMed
  34. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  35. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  36. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. D'Alessandro G, et al. 2020. Eur J Immunol. 50:705. PubMed
  2. DeSouza-Vieira T, et al. 2020. Cell Rep. 33:108317. PubMed
  3. Gogoi H, et al. 2020. Front Immunol. 1.620833333. PubMed
  4. Liu K, et al. 2021. Cell Metabolism. 33(3):666-675.e4. PubMed
  5. Wang L, et al. 2021. J Nanobiotechnology. 19:56. PubMed
  6. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  7. Kuo PC, et al. 2021. Brain Commun. 3:fcab187. PubMed
  8. Rosina M, et al. 2022. Cell Metab. 34:533. PubMed
  9. Cheresh P, et al. 2021. Int J Mol Sci. 22:. PubMed
  10. Deng R, et al. 2022. Adv Sci (Weinh). 9:e2103343. PubMed
  11. Odom CV, et al. 2021. J Immunol. 207:1891. PubMed
  12. Hatzi K, et al. 2019. Nat Immunol. 20:86. PubMed
  13. Tran NT, et al. 2019. Cell Rep. 28:3510. PubMed
  14. Lin C et al. 2019. Immunity. 50(1):137-151 . PubMed
  15. Okunuki Y, et al. 2018. Proc Natl Acad Sci U S A. 115:E6264. PubMed
  16. Denny L, et al. 2021. Clin Transl Immunology. 10:e1234. PubMed
  17. Janbandhu V, et al. 2022. Cell Stem Cell. 29:281. PubMed
  18. Cohen K, et al. 2021. Cell Rep. 37:110026. PubMed
  19. Aimaitijiang A, et al. 2022. Genes Cells. 27:25. PubMed
  20. Schnell A, et al. 2021. Cell. 184:6281. PubMed
  21. Zhou Y, et al. 2022. Br J Pharmacol. 179:1978. PubMed
  22. Hiyoshi H, et al. 2022. Cell Host Microbe. 30:163. PubMed
  23. Wang B, et al. 2022. EMBO J. 41:e108946. PubMed
  24. Wang S, et al. 2022. Sci Adv. 8:eabn3883. PubMed
  25. Du Y, et al. 2022. J Exp Med. 219: . PubMed
  26. Pannunzio B, et al. 2022. Cells. 11: . PubMed
  27. Marié IJ, et al. 2022. Bio Protoc. 12:e4438. PubMed
  28. Hong Y, et al. 2022. J Leukoc Biol. 112:425. PubMed
  29. Que W, et al. 2022. Sci Adv. 8:eabo4413. PubMed
  30. Liu Z, et al. 2022. Cancer Commun (Lond). 42:971. PubMed
  31. Zhang X, et al. 2022. EBioMedicine. 84:104275. PubMed
  32. Hindy G, et al. 2022. J Clin Invest. 132: . PubMed
  33. Lu Z, et al. 2022. Cell Rep. 41:111482. PubMed
  34. Mansouri S, et al. 2022. J Immunol. 209:2114. PubMed
  35. Yoo HJ, et al. 2022. Cell Rep. 41:111598. PubMed
  36. Papaxenopoulou LA, et al. 2022. iScience. 25:105522. PubMed
  37. Zhang Y, et al. 2022. Front Oncol. 12:1042250. PubMed
  38. He Y, et al. 2022. Front Immunol. 13:986202. PubMed
  39. Lee DE, et al. 2022. Nat Commun. 13:7613. PubMed
  40. Kraemer AN, et al. 2022. Front Immunol. 13:933191. PubMed
  41. Choi H, et al. 2023. J Nanobiotechnology. 21:5. PubMed
  42. Wang D, et al. 2023. J Exp Clin Cancer Res. 42:26. PubMed
  43. Leinenga G, et al. 2023. Bioeng Transl Med. 8:e10329. PubMed
  44. Wang R, et al. 2023. iScience. 26:105954. PubMed
  45. Slusarczyk P, et al. 2023. Elife. 12: . PubMed
  46. Ernst MPT, et al. 2023. Hemasphere. 7:e824. PubMed
  47. Drijvers JM, et al. 2021. Cancer Immunol Res. 9:184. PubMed
  48. Yeh CH, et al. 2022. Immunity. 55:272. PubMed
  49. Sheng YH, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:789. PubMed
  50. Banerjee K, et al. 2023. Eur J Immunol. 53:e2250161. PubMed
  51. Mela V, et al. 2023. Mol Neurobiol. 60:3044. PubMed
  52. Schönberger K, et al. 2023. Anal Chem. 95:4325. PubMed
  53. Li L, et al. 2023. iScience. 26:106095. PubMed
  54. Tang C, et al. 2023. Nat Commun. 14:1493. PubMed
  55. Gupta T, et al. 2023. Front Immunol. 14:1044703. PubMed
  56. MacPherson KP, et al. 2023. Front Cell Neurosci. 17:895017. PubMed
  57. Martins Nascentes Melo L, et al. 2023. J Immunother Cancer. 11:. PubMed
  58. Pastrez PRA, et al. 2023. Cancers (Basel). 15:. PubMed
  59. Yao H, et al. 2023. Front Immunol. 14:1147674. PubMed
  60. Hernandez VG, et al. 2023. Glia. 71:1960. PubMed
  61. Kim BH, et al. 2023. Sci Rep. 13:6577. PubMed
  62. Lu Y, et al. 2023. J Transl Med. 21:339. PubMed
  63. Bobadilla Muñoz M, et al. 2023. Front Cell Dev Biol. 11:1128534. PubMed
  64. Doloff JC, et al. 2023. Sci Adv. 9:eade9488. PubMed
  65. Ye S, et al. 2023. Front Oncol. 13:1202750. PubMed
  66. Parsons M, et al. 2014. J Immunol. 192:1361. PubMed
  67. Tebartz C, et al. 2015. J Immunol. 194:1100. PubMed
  68. Quispe Calla N, et al. 2016. Sci Rep. 6:37723. PubMed
  69. Li Z, et al. 2021. Immunology. 163:105. PubMed
  70. Correa S, et al. 2020. ACS Nano. 14:2224. PubMed
  71. Kim JS, et al. 2020. Immunity. 54(1):176-190.e7. PubMed
  72. Giorgetti E, et al. 2020. Cell Reports. 29(6):1539-1554.e7.. PubMed
  73. Thelin MA, et al. 2017. Diabetes. 66:2220. PubMed
  74. Rodrigues M, et al. 2022. Biochem J. 479:1891. PubMed
  75. Jung MY, et al. 2022. Neurooncol Adv. 4:vdac017. PubMed
  76. Schönberger K, et al. 2022. Cell Stem Cell. 29:131. PubMed
  77. Di Martile M, et al. 2020. J Immunother Cancer. 8:. PubMed
  78. Sharma GP, et al. 2021. PLoS One. 16:e0259042. PubMed
  79. Zhang LJ, et al. 2019. Immunity. 50:121. PubMed
  80. Abels ER et al. 2019. Cell Rep. 28(12):3105-3119 . PubMed
  81. Frisbee AL, et al. 2019. Nat Commun. 10:2712. PubMed
  82. Groza D, et al. 2018. Oncoimmunology. 7:e1424676. PubMed
  83. Alissafi T, et al. 2018. J Clin Invest. 128:3840. PubMed
  84. Iwamoto H et al. 2018. Cell metabolism. 28(1):104-117 . PubMed
  85. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  86. Kitagawa S, et al. 2022. NPJ Vaccines. 7:115. PubMed
  87. Gazit R, et al. 2014. J Exp Med. 211:1315. PubMed
  88. Zheng W, et al. 2021. Wellcome Open Research. 6:52. PubMed
  89. Mogilenko DA, et al. 2020. Immunity. 54(1):99-115.e12. PubMed
  90. Riether C, et al. 2021. Cell Reports. 34(4):108663. PubMed
  91. Yu K, et al. 2021. Cell Reports. 35(12):109273. PubMed
  92. Wei H, et al. 2021. Malar J. 20:89. PubMed
  93. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 5:64. PubMed
  94. Hickey A, et al. 2021. Front Microbiol. 12:653587. PubMed
  95. Delás MJ, et al. 2019. Cell Rep. 27:719. PubMed
  96. Morgan PK, et al. 2021. J Biol Chem. 297:101341. PubMed
  97. Yang C, et al. 2021. J Immunother Cancer. 9:. PubMed
  98. Piepke M, et al. 2021. J Neuroinflammation. 18:265. PubMed
  99. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  100. Chen T, et al. 2021. JCI Insight. 6:. PubMed
  101. Kurelac I, et al. 2019. Nat Commun. 10:903. PubMed
  102. Kobayashi Y, et al. 2018. PLoS One. 13:e0195008. PubMed
  103. Radovanovic I, et al. 2014. J Immunol. 193:1290. PubMed
  104. Zasłona Z, et al. 2014. J Immunol. 193:4245. PubMed
  105. Yang X, et al. 2020. Blood Sci. 2:89. PubMed
  106. Deslyper G, et al. 2021. Parasitology. 148:539. PubMed
  107. Periasamy S, et al. 2017. Nat Commun. 8:15564. PubMed
  108. Saggu G, et al. 2018. Nat Commun. 9:5058. PubMed
  109. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  110. Bowers E, et al. 2018. Nat Med. 24:95. PubMed
  111. Shen H, et al. 2015. Infect Immun . 83: 2694 - 2704. PubMed
  112. Shemer A, et al. 2020. Immunity. 53(5):1033-1049.e7. PubMed
  113. Yamamoto K, et al. 2021. Cell Reports. 36(8):109576. PubMed
  114. Uroda T, et al. 2020. Nat Protoc. 15:2107. PubMed
  115. Go DM, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:715. PubMed
  116. Park JA, et al. 2021. J Hematol Oncol. 14:142. PubMed
  117. Zong L, et al. 2021. NPJ Aging Mech Dis. 7:25. PubMed
  118. LaFleur MW, et al. 2019. Nat Immunol. 20:1335. PubMed
  119. Somerville TD, et al. 2020. eLife. 9:e53381.. PubMed
  120. Almutairi F, et al. 2021. Front Immunol. 12:772288. PubMed
  121. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  122. Akhmetzyanova ER, et al. 2019. Front Cell Neurosci. 12:507. PubMed
  123. Lubkin A et al. 2019. Cell host & microbe. 25(3):463-470 . PubMed
  124. Gibson EM, et al. 2019. Cell. 176:43:00. PubMed
  125. Juttukonda LJ, et al. 2017. Cell Host Microbe. 22:531. PubMed
  126. Royzman D, et al. 2022. Front Immunol. 13:1012647. PubMed
  127. Martin R, et al. 2014. J Leukoc Biol. 96:151. PubMed
  128. Super M, et al. 2021. Nat Biomed Eng. Online ahead of print. PubMed
  129. Kulkarni NN, et al. 2021. J Biol Chem. 297:100828. PubMed
  130. Jia X, et al. 2021. Front Cell Dev Biol. 9:685522. PubMed
  131. Klopfenstein N, et al. 2021. PLoS Pathog. 17:e1009387. PubMed
  132. Xu X, et al. 2021. J Nanobiotechnology. 19:376. PubMed
  133. Walker FC, et al. 2021. PLoS Pathog. 17:e1009402. PubMed
  134. Johansen AZ, et al. 2022. Pharmaceutics. 14:. PubMed
  135. Liu Y, et al. 2022. Nat Commun. 13:2665. PubMed
  136. Beauchamp EM, et al. 2021. Blood Cancer Discov. 6:. PubMed
  137. Dodagatta-Marri E, et al. 2021. Cell Rep. 36:109309. PubMed
  138. Sasaki K, et al. 2019. Nat Commun. 10:3878. PubMed
  139. Angelidis I, et al. 2019. Nat Commun. 10:963. PubMed
  140. Ellis G, et al. 2015. EMBO Rep. 16: 1203-1218. PubMed
  141. Vazquez S, et al. 2015. Exp Hematol. 43: 578-585. PubMed
  142. Shade K, et al. 2015. J Exp Med. 212:457. PubMed
  143. Kohn M, et al. 2021. Front Immunol. 580594:12. PubMed
  144. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  145. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  146. Wang L, et al. 2021. Cancer Immunol Res. 9:348. PubMed
  147. Meeks K, et al. 2009. J Immunol. 183:8026. PubMed
  148. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  149. Shin JE, et al. 2021. Heliyon. 7:e08433. PubMed
  150. Vasilijevic J, et al. 2017. PLoS Pathog. 13:e1006650. PubMed
  151. Koh F, et al. 2015. Proc Natl Acad Sci U S A. 112:1734. PubMed
  152. Pan YC, et al. 2021. Mol Ther Oncolytics. 20:175. PubMed
  153. Aegerter H, et al. 2020. Nat Immunol. 0.975694444. PubMed
  154. Zhang S, et al. 2020. Front Immunol. 1.757638889. PubMed
  155. Amo-Aparicio J, et al. 2021. Theranostics. 11:9805. PubMed
  156. Mansouri S, et al. 2021. J Immunol. 206:2233. PubMed
  157. Goldman E, et al. 2021. Cells. 10:. PubMed
  158. Dokoshi T, et al. 2021. J Clin Invest. 131:. PubMed
  159. Varol D et al. 2017. Immunity. 46(6):1030-1044 . PubMed
  160. Snell LM, et al. 2018. Immunity. 49:678. PubMed
  161. Kirschbaum K, et al. 2016. Proc Natl Acad Sci U S A. 113: 13227 - 13232. PubMed
  162. Xie Z, et al. 2020. Light Sci Appl. 0.486805556. PubMed
  163. Gomzikova MO, et al. 2020. Sci Rep. 10:10740. PubMed
  164. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  165. Okubo K, et al. 2021. Cell Reports. 35(7):109142. PubMed
  166. Gozgit JM, et al. 2021. Cancer Cell. :. PubMed
  167. Huang YL, et al. 2021. Commun Biol. 4:229. PubMed
  168. Littwitz-Salomon E, et al. 2021. Nat Commun. 12:5376. PubMed
  169. Synn CB, et al. 2022. Clin Transl Immunology. 11:e1364. PubMed
  170. Kooreman NG et al. 2018. Cell stem cell. 22(4):501-513 . PubMed
  171. Proto JD et al. 2018. Immunity. 49(4):666-677 . PubMed
  172. Secondini C, et al. 2017. Oncoimmunology. 6:e1316437. PubMed
  173. Wang D, et al. 2021. Nat Commun. 12:2674. PubMed
  174. Jia Q, et al. 2021. Theranostics. 4699:11. PubMed
  175. Dobosz E, et al. 2021. Dis Model Mech. :14. PubMed
  176. Mulas F, et al. 2020. Cell Mol Immunol. . PubMed
  177. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  178. Bambouskova M, et al. 2021. Cell Reports. 34(10):108756. PubMed
  179. Ringel AE, et al. 2020. Cell. 183(7):1848-1866.e26. PubMed
  180. Suresh MV, et al. 2019. JCI Insight. 4:e133103. PubMed
  181. Patel S, et al. 2019. Viruses. 0.877083333. PubMed
  182. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  183. Uddin MJ, et al. 2022. Mucosal Immunol. 15:165. PubMed
  184. Bradley KC, et al. 2019. Cell Rep. 28:245. PubMed
  185. Kumar MP, et al. 2018. Cell Rep. 25:1458. PubMed
  186. Steuerman Y et al. 2018. Cell systems. 6(6):679-691 . PubMed
  187. Pérez-Girón J, et al. 2015. J Vis Exp. 100: 52803. PubMed
  188. Trefzer A, et al. 2021. Cell Reports. 34(6):108748. PubMed
  189. Lim CX, et al. 2020. Cell Rep. 3793:30. PubMed
  190. Wilson DH, et al. 2020. Nat Commun. 0.767361111. PubMed
  191. Tran NT, et al. 2020. STAR Protocols. 1(1):100028. PubMed
  192. Endoh M, et al. 2020. Cell Reports. 30(6):1823-1834. PubMed
  193. Li H, et al. 2020. Nature. 584:274. PubMed
  194. Sibilio A, et al. 2022. iScience. 25:103790. PubMed
  195. Dey S, et al. 2020. J Immunother Cancer. 8:. PubMed
  196. Shen M, et al. 2022. Nat Cancer. 3:60. PubMed
  197. Li Z, et al. 2018. Front Immunol. 9:347. PubMed
  198. Marcus A et al. 2018. Immunity. 49(4):754-763 . PubMed
  199. Van Winkle JA et al. 2018. Cell host & microbe. 24(5):665-676 . PubMed
  200. LaFleur MW, et al. 2019. Nat Commun. 10:1668. PubMed
  201. Liu H, et al. 2022. Front Pharmacol. 13:949316. PubMed
  202. Boulay A, et al. 2015. J Neurosci. 35:4427. PubMed
  203. Monaghan KL, et al. 2020. J Vis Exp. . PubMed
  204. Frenis K, et al. 2021. Basic Res Cardiol. 31:116. PubMed
  205. Crouse B, et al. 2020. NPJ Vaccines. 0.277083333. PubMed
  206. Choi EW, et al. 2020. Sci Rep. 10:12001. PubMed
  207. Denny JE, et al. 2019. Sci Rep. 2.786111111. PubMed
  208. Liu C et al. 2019. Immunity. 51(2):381-397 . PubMed
  209. Simula L et al. 2018. Cell reports. 25(11):3059-3073 . PubMed
  210. Gao C, et al. 2017. Mol Neurobiol.. 10.1007/s12035-016-0318-0. PubMed
  211. Khare P, et al. 2017. J Autoimmun. 10.1016/j.jaut.2017.09.002. PubMed
  212. Lee L, et al. 2016. PLoS One. 11:e0167693. PubMed
  213. Arce-Cerezo A, et al. 2015. Sci Rep. 5: 1448. PubMed
  214. Ballet R, et al. 2014. PLoS Pathog. 10:1004550. PubMed
  215. Koelwyn GJ, et al. 2020. Nat Med. 1452:26. PubMed
  216. Kim SJ, et al. 2020. Cell Mol Immunol. 17:728. PubMed
  217. Nowlan B, et al. 2019. Haematologica. 105:71. PubMed
  218. Mohamed E, et al. 2020. Immunity. 52(4):668-682.e7.. PubMed
  219. Wuggenig P, et al. 2020. Commun Biol. 3:130. PubMed
  220. Merrell AJ, et al. 2021. Hepatology. 74:444. PubMed
  221. Chen C, et al. 2021. J Virol. 95:e0082921. PubMed
  222. Yu W, et al. 2022. Nat Commun. 13:3544. PubMed
  223. Robinett RA et al. 2018. Cell systems. 7(1):41-48 . PubMed
  224. Scholz F, et al. 2015. J Immunol. 195: 2335-2342. PubMed
  225. Nahrendorf W, et al. 2021. eLife. 10:00. PubMed
  226. Mansouri S, et al. 2020. Mucosal Immunol. 0.954861111. PubMed
  227. Kalafati L, et al. 2020. Cell. 183:771. PubMed
  228. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  229. Zhang CR, et al. 2022. Blood Cancer Discov. 3:220. PubMed
  230. Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
  231. Wang S, et al. 2021. Commun Biol. 22:. PubMed
  232. Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
  233. Song J, et al. 2021. Am J Physiol Heart Circ Physiol. 320:H323. PubMed
  234. Bent EH, et al. 2021. Nat Commun. 12:6218. PubMed
  235. Duarte D, et al. 2018. Cell Stem Cell. 22:64. PubMed
  236. Sasaki Y, et al. 2015. PLoS One. 10: 0131176. PubMed
  237. Kobia FM, et al. 2020. PLoS Biol. 18:e3000850. PubMed
  238. Bordas M, et al. 2020. Int J Mol Sci. 21:00. PubMed
  239. Bellomo A, et al. 2020. Immunity. 53(1):127-142.e7. PubMed
  240. Jiang L, et al. 2020. Cell. 183(5):1219-1233.e18. PubMed
  241. Onai N, et al. 2020. Int J Mol Sci. :22. PubMed
  242. Ivan DC, et al. 2021. Front Immunol. 12:666961. PubMed
  243. Yousef H, et al. 2019. Nat Med. 25:988. PubMed
  244. Franklin DA, et al. 2020. JCI Insight. 5:. PubMed
  245. Omatsu Y, et al. 2022. Nat Commun. 13:2654. PubMed
  246. Liu W, et al. 2022. J Clin Invest. 132: . PubMed
  247. Schönberger K, et al. 2022. STAR Protoc. 3:101408. PubMed
  248. Celik H, et al. 2018. Cancer Cell. 34:741. PubMed
  249. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  250. Njock MS, et al. 2022. J Extracell Vesicles. 11:e12228. PubMed
  251. Calderon B, et al. 2015. J Exp Med. 212: 1497-1512. PubMed
  252. Richardson ET, et al. 2015. PLoS One. 10: 1371. PubMed
  253. Moro T, et al. 2016. PLoS One. 11: 0146592. PubMed
  254. Johnson RM, et al. 2021. Front Immunol. 11:614697. PubMed
  255. Kiss M, et al. 2020. Cancer Immunol Res. 9:309. PubMed
  256. Gourvest M, et al. 2021. Leukemia. . PubMed
  257. Bagati A, et al. 2020. Cancer Cell. 39(1):54-67.e9. PubMed
  258. Beauchamp N, et al. 2010. J Virol. 84:10191. PubMed
  259. Wang Y, et al. 2020. eLife. 9:e57438.. PubMed
  260. Yu L, et al. 2020. Nat Commun. 2.045833333. PubMed
  261. Sadhu S, et al. 2021. J Immunol. 207:1812. PubMed
  262. Sun L, et al. 2022. Adv Sci (Weinh). 9:e2104051. PubMed
  263. Canedo T, et al. 2021. Neuropsychopharmacology. 46:2358. PubMed
  264. McKenzie MD, et al. 2019. Cell Stem Cell. 25:258. PubMed
  265. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  266. Contreras NA, et al. 2019. PLoS Pathog. 15:e1007890. PubMed
  267. Cantor DJ et al. 2019. Cell reports. 26(1):108-118 . PubMed
  268. Baratin M, et al. 2017. Immunity. 47:349. PubMed
  269. Coley WD et al. 2018. F1000Research. 2018 Mar 14 [revised 2018 Jan 1] 0.5125. PubMed
  270. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  271. Gicheva N, et al. 2016. Biochem Biophys Res Commun. 479:1-4. PubMed
  272. Tsunekuni K, et al. 2020. J Clin Med. 9:00. PubMed
  273. Huang WC, et al. 2020. Adv Mater. 32:e2005637. PubMed
  274. Shin M, et al. 2020. Cell Chem Biol. 314:27. PubMed
  275. Kaiser S, et al. 2020. Glia. 68:2427. PubMed
  276. Aggio-Bruce R, et al. 2020. Mol Neurobiol. . PubMed
  277. Santopaolo M, et al. 2021. Front Immunol. 609406:12. PubMed
  278. Molgora M, et al. 2020. Cell. 182:886. PubMed
  279. Rosen DA, et al. 2019. Sci Transl Med. 11:eaau5266. PubMed
  280. Dokoshi T, et al. 2020. Cell Rep. 30:61. PubMed
  281. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 0.252777778. PubMed
  282. Süß P, et al. 2020. Cell Reports. 30(12):4082-4095. PubMed
  283. Shi J, et al. 2022. Front Pharmacol. 12:818326. PubMed
  284. Asada S, et al. 2018. Nat Commun. 9:2733. PubMed
  285. Kong XF, et al. 2018. Nat Immunol. 19:973. PubMed
  286. McPhee C, et al. 2013. J Immunol. 191:4581. PubMed
  287. Fujimura N, et al. 2016. Sci Rep. 5:11664. PubMed
  288. Gao P, et al. 2020. Front Immunol. 1.636111111. PubMed
  289. Alfaro M, et al. 2008. Proc Natl Acad Sci U S A. 105:18366. PubMed
  290. Liu G, et al. 2022. Theranostics. 12:2248. PubMed
  291. Fan HH, et al. 2021. Methods Mol Biol. 2276:203. PubMed
  292. Monteiro LB, et al. 2020. MethodsX. 7:100938. PubMed
  293. Rodriguez-Tirado C, et al. 2022. Cancers (Basel). 14:. PubMed
  294. Lau P, et al. 2022. Cell Mol Immunol. :. PubMed
  295. Harding CL, et al. 2020. Front Cell Infect Microbiol. 10:328. PubMed
  296. Chavez JS, et al. 2022. Cells. 11:. PubMed
  297. Boulch M, et al. 2021. Sci Immunol. 6:. PubMed
  298. Walker JA, et al. 2020. Immunity. 51(1):104-118. PubMed
  299. Winter C, et al. 2018. Cell Metab. 28:175. PubMed
  300. Tippimanchai DD, et al. 2018. Oncoimmunology. 7:e1438105. PubMed
  301. Chen S, et al. 2015. Cancer Res . 7: 519-531. PubMed
  302. Groppa E, et al. 2015. EMBO Mol Med. 2015; 7: 1366 - 1384. PubMed
  303. Gharib S, et al. 2014. J Leukoc Biol. 95:9. PubMed
  304. Akhand SS, et al. 2020. Cancer Immunol Res. 8:1542. PubMed
  305. Boguslawski KM, et al. 2020. Sci Adv. 6:eaax7515. PubMed
  306. Wang L, et al. 2020. J Nanobiotechnology. 18:38. PubMed
  307. Mansouri S, et al. 2021. J Immunol. 206:2233. PubMed
  308. Franklin R, et al. 2022. Nat Commun. 13:2350. PubMed
  309. Gawish R, et al. 2022. Elife. 11:. PubMed
  310. Saul S, et al. 2019. J Leukoc Biol. N/A. PubMed
  311. Severe N et al. 2019. Cell Stem Cell. 25(4):570-583 . PubMed
  312. Xu G, et al. 2015. Free Radic Biol Med. 87: 15-25. PubMed
  313. Zhang S, et al. 2016. PLoS Pathog. 12: 1005617. PubMed
  314. Xie Z, et al. 2020. Light Sci Appl. 9:161. PubMed
  315. Zhang B, et al. 2021. Front Neurol. 607370:12. PubMed
  316. Young K, et al. 2021. Cell Stem Cell. . PubMed
  317. Lucas ED, et al. 2020. Cell Reports. 33(2):108258. PubMed
  318. Huanga J, et al. 2013. J Immunol Methods. 387:254. PubMed
  319. Maas SLN, et al. 2020. J Neuroinflammation. 17:120. PubMed
  320. Qi S, et al. 2020. Theranostics. 10:1814. PubMed
  321. Zheng W, et al. 2019. Cell Rep. 29:1747. PubMed
  322. Zhang Y, et al. 2022. J Immunother Cancer. 10:. PubMed
  323. Wang Y, et al. 2022. Nat Cell Biol. 24:230. PubMed
  324. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  325. Lalor R, et al. 2019. Nutrients. 11. PubMed
  326. Cai T, et al. 2022. Front Immunol. 13:1009932. PubMed
  327. Scheyltjens I, et al. 2022. Nat Protoc. 17:2354. PubMed
  328. Zysset D, et al. 2016. Nat Commun. 7:13151. PubMed
RRID
AB_312798 (BioLegend Cat. No. 101215)
AB_312799 (BioLegend Cat. No. 101216)

Antigen Details

Structure
Integrin family, associates with integrin β2 (CD18), 170 kD
Distribution

Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subsets of T and B cells

Function
Adhesion, chemotaxis
Ligand/Receptor
ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen
Cell Type
B cells, Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653.

Gene ID
16409 View all products for this Gene ID 3684 View all products for this Gene ID
UniProt
View information about CD11b on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD11b Reagents Request Custom Conjugation
Description Clone Applications
PE/Cyanine7 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 750 anti-mouse/human CD11b M1/70 FC
TotalSeq™-A0014 anti-mouse/human CD11b M1/70 PG
Brilliant Violet 750™ anti-mouse/human CD11b M1/70 FC
TotalSeq™-C0014 anti-mouse/human CD11b M1/70 PG
TotalSeq™-B0014 anti-mouse/human CD11b M1/70 PG
Spark NIR™ 685 anti-mouse/human CD11b M1/70 FC
PE/Fire™ 640 anti-mouse/human CD11b M1/70 FC
APC anti-mouse/human CD11b M1/70 FC
Biotin anti-mouse/human CD11b M1/70 FC
FITC anti-mouse/human CD11b M1/70 FC
PE anti-mouse/human CD11b M1/70 FC,IHC
PE/Cyanine5 anti-mouse/human CD11b M1/70 FC
Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,IHC-F,ICC
Alexa Fluor® 488 anti-mouse/human CD11b M1/70 FC,IHC-F,3D IHC,SB
Alexa Fluor® 647 anti-mouse/human CD11b M1/70 FC,3D IHC,SB
Alexa Fluor® 700 anti-mouse/human CD11b M1/70 FC
Pacific Blue™ anti-mouse/human CD11b M1/70 FC
APC/Cyanine7 anti-mouse/human CD11b M1/70 FC
PerCP/Cyanine5.5 anti-mouse/human CD11b M1/70 FC
PerCP anti-mouse/human CD11b M1/70 FC
Brilliant Violet 421™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 570™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 605™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 650™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 711™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 785™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 510™ anti-mouse/human CD11b M1/70 FC,ICC
Ultra-LEAF™ Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,Block,Depletion,IHC-F,ICC
Purified anti-mouse/human CD11b (Maxpar® Ready) M1/70 FC,CyTOF®
Alexa Fluor® 594 anti-mouse/human CD11b M1/70 IHC-F,FC
PE/Dazzle™ 594 anti-mouse/human CD11b M1/70 FC
Spark YG™ 593 anti-mouse/human CD11b M1/70 FC
Spark YG™ 570 anti-mouse/human CD11b M1/70 IHC-F
PE/Fire™ 810 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 810 anti-mouse/human CD11b Antibody M1/70 FC
Spark Blue™ 550 anti-mouse/human CD11b M1/70 FC
Spark UV™ 387 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 806 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 780 anti-mouse/human CD11b M1/70 FC
Spark Blue™ 574 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
KIRAVIA Blue 520™ anti-mouse/human CD11b M1/70 FC
PE/Fire™ 744 anti-mouse/human CD11b M1/70 FC
Spark PLUS UV395™ anti-mouse/human CD11b M1/70 FC
Spark Red™ 718 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
Spark PLUS B550™ anti-mouse/human CD11b M1/70 FC
Spark YG™ 581 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
StarBright UltraViolet 575 anti-mouse/human CD11b M1/70 FC
StarBright UltraViolet 740 anti-mouse/human CD11b M1/70 FC
Spark PLUS V475™ anti-mouse/human CD11b M1/70 FC
Spark PLUS YG581™ anti-mouse/human CD11b M1/70 FC
Spark PLUS V450™ anti-mouse/human CD11b M1/70 FC
Go To Top Version: 1    Revision Date: 11-30-2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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