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PerCP/Cyanine5.5 anti-mouse/human CD11b Antibody

Pricing & Availability
Clone
M1/70 (See other available formats)
Regulatory Status
RUO
Other Names
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
Isotype
Rat IgG2b, κ
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Product Citations
publications
M1slash70_PerCPCyanine55_CD11b_Antibody_111918
C57BL/6 splenocytes were blocked with TruStain FcX™ (anti-mouse CD16/32) Antibody then stained with Ly-6G/Ly-6C (Gr-1) APC and CD11b (clone M1/70) PerCP/Cyanine5.5 (left) or rat IgG2b, κ PerCP/Cyanine5.5 isotype control (right).
  • M1slash70_PerCPCyanine55_CD11b_Antibody_111918
    C57BL/6 splenocytes were blocked with TruStain FcX™ (anti-mouse CD16/32) Antibody then stained with Ly-6G/Ly-6C (Gr-1) APC and CD11b (clone M1/70) PerCP/Cyanine5.5 (left) or rat IgG2b, κ PerCP/Cyanine5.5 isotype control (right).
Compare all formats See PerCP/Cyanine5.5 spectral data
Cat # Size Price Quantity Check Availability Save
101227 25 µg 72€
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101228 100 µg 234€
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Description

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human, Cynomolgus, Rhesus
Reported Reactivity
Chimpanzee, Baboon, Rabbit
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
C57BL/10 splenocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PerCP/Cyanine5.5 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The CD11b antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F).

Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1,4, in vitro blocking3,9,12, depletion2,8, immunofluorescence microscopy6,7,10, immunohistochemistry of acetone-fixed frozen sections5,11-13, and spatial biology (IBEX)35,36. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).

Application References

(PubMed link indicates BioLegend citation)
  1. Springer T, et al. 1978. Eur. J. Immunol. 8:539. (IP)
  2. Ault K and Springer T. 1981. J. Immunol. 126:359. (Deplete)
  3. Springer TA, et al. 1982. Immunol. Rev. 68:171. (Block)
  4. Ho MK and Springer TA. 1983. J. Biol. Chem. 258:2766. (IP)
  5. Flotte TJ, et al. 1983. Am. J. Pathol. 111:112. (IHC)
  6. Noel GJ, et al. 1990. J. Clin. Invest. 85:208. (IF)
  7. Allen LA and Aderem A. 1996. J. Exp. Med. 184:627 (IF)
  8. D'Amico A and Wu L. 2003. J. Exp. Med. 198:293. (Deplete)
  9. Brickson SJ, et al. 2003. Appl Physiol. 95:969. (Block)
  10. Clatworthy MR and Smith KG. 2004. J. Exp. Med. 199:717. (IF)
  11. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  12. Zhang Y, et al. 2002. J. Immunol. 168:3088. (IHC)
  13. Iwasaki A and Kelsall BL. 2001. J. Immunol. 166:4884 (IHC, FC)
  14. Tailleux L. 2003. J. Exp. Med. 197:121. (Block, FC)
  15. Olver S, et al. 2006. Cancer Research 66:571. (FC)
  16. Tan SL, et al. 2006. J. Immunol. 176:2872. (FC) PubMed
  17. Ponomarev ED, et al. 2006. J. Immunol. 176:1402. (FC)
  18. Dzhagalov I, et al. 2007. Blood 109:1620. (FC)
  19. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  20. Rasmussen JW, et al. 2006. Infect. Immun.74:6590. PubMed
  21. Napimoga MH, et al. 2008. J. Immunol. 180:609. PubMed
  22. Elqaraz-Carmon V, et al. 2008. J. Lipid. Res. 49:1894. PubMed
  23. Kim DD, et al. 2008. Blood 112:1109. PubMed
  24. Guo Y, et al. 2008. Blood 112:480. PubMed
  25. Norian LA, et al. 2009. Cancer Res. 69:3086. (FC) PubMed
  26. Baumgartner CK, et al. 2010. J. Immunol. 184:573. PubMed
  27. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  28. Whiteland J, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
  29. Weber GF, et al. 2014. J Exp Med. 211:1243. PubMed
  30. Ashok A, et al. 2015. Toxicol Sci. 143:64. PubMed
  31. Price PJ, et al. 2015. J Immunol. 194:1164. PubMed
  32. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  33. Ferreira R, et al. 2016. J Infect Dis. 213: 669 - 673. PubMed
  34. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  35. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  36. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Lee T, et al. 2014. Mol Biol Cell. 25:583. PubMed
  2. Guo H, Cooper S, Friedman A, et al. 2017. PLoS One. 10.1371/journal.pone.0150809. PubMed
  3. Orberg E, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.53. PubMed
  4. Lang J, et al. 2020. Nat Commun. 11:1338. PubMed
  5. Gordan S, et al. 2020. Cell Reports. 29(10):3033-3046.e4.. PubMed
  6. Milasan A, et al. 2017. J Am Heart Assoc. 10.1161/JAHA.117.006892. PubMed
  7. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  8. Tian WJ, et al. 2021. Clin Exp Pharmacol Physiol. 48:902. PubMed
  9. Ferrao Blanco MN, et al. 2022. Br J Pharmacol. 179:2771. PubMed
  10. Osokine I, et al. 2022. Cell Rep. 38:110329. PubMed
  11. Agarwalla P, et al. 2022. Nat Biotechnol. 40:1250. PubMed
  12. Chae CS, et al. 2022. Cancer Discov. 12:1904. PubMed
  13. Yang K, et al. 2022. Sci Immunol. 7:eabn2888. PubMed
  14. Marquardt RM, et al. 2022. Int J Mol Sci. 23: . PubMed
  15. Halin C, et al. 2022. EMBO J. 41:e111528. PubMed
  16. Auguste YSS, et al. 2022. Nat Neurosci. 25:1273. PubMed
  17. Schepers M, et al. 2023. Brain Behav Immun. 109:1. PubMed
  18. García-García A, et al. 2023. Bioact Mater. 24:174. PubMed
  19. Glaubitz J, et al. 2023. Gut. :. PubMed
  20. Zhang K, et al. 2023. Nat Metab. 5:129. PubMed
  21. Arimoto KI, et al. 2023. Nat Commun. 14:251. PubMed
  22. Zhang B, et al. 2023. Signal Transduct Target Ther. 8:28. PubMed
  23. Lazure F, et al. 2023. Nat Commun. 14:535. PubMed
  24. Murakata Y, et al. 2023. Front Cardiovasc Med. 9:1075358. PubMed
  25. Meng S, et al. 2023. Stem Cell Investig. 10:2. PubMed
  26. Drummer C, et al. 2023. Front Immunol. 14:1113883. PubMed
  27. Peng W, et al. 2022. Cell Mol Life Sci. 79:602. PubMed
  28. Chen H, et al. 2023. Nat Commun. 14:941. PubMed
  29. Zhu S, et al. 2023. J Nanobiotechnology. 21:81. PubMed
  30. Guo D, et al. 2023. Cell Biosci. 13:51. PubMed
  31. Kozlovski S, et al. 2023. Front Immunol. 13:1041552. PubMed
  32. Do-Thi VA, et al. 2023. Cancer Res Commun. 3:80. PubMed
  33. Shen Z, et al. 2023. iScience. 26:106572. PubMed
  34. Haensel D, et al. 2023. Nat Commun. 14:2685. PubMed
  35. Wilden A, et al. 2022. Front Immunol. 13:991295. PubMed
  36. Zhou R, et al. 2022. EBioMedicine. 75:103762. PubMed
  37. Grandjean CL, et al. 2021. Sci Adv. 7:. PubMed
  38. Leslie J, et al. 2021. Sci Rep. 11:1415. PubMed
  39. Zheng J, et al. 2022. Front Pharmacol. 13:866228. PubMed
  40. Zhu Y, et al. 2022. Nat Commun. 13:4282. PubMed
  41. Li Z, et al. 2022. Nat Commun. 13:1845. PubMed
  42. Liu Y, et al. 2021. Cell Metabolism. 33(6):1221-1233.e11. PubMed
  43. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  44. John S, et al. 2020. Sci Rep. 10:11377. PubMed
  45. Hastings AK, et al. 2019. iScience. 13:339. PubMed
  46. Kim SS, et al. 2022. Cancers (Basel). 14:. PubMed
  47. Hofmann I, et al. 2022. J Pharmacol Exp Ther. Online ahead of print. PubMed
  48. Huang X, et al. 2021. Stem Cells Int. 2021:8138374. PubMed
  49. Hong M, et al. 2021. Int J Mol Sci. 22:. PubMed
  50. Li X, et al. 2022. Nat Commun. 13:2794. PubMed
  51. Zhao X, et al. 2022. Front Mol Biosci. 9:786864. PubMed
  52. Meng W, et al. 2021. JCI Insight. 6:. PubMed
  53. Ortiz G, et al. 2020. Front Immunol. 11:1713. PubMed
  54. McNamara HA, et al. 2020. Cell Host Microbe. 572:28. PubMed
  55. Bouchareychas L, et al. 2021. iScience. 24(8):102847. PubMed
  56. Gern BH, et al. 2021. Cell Host Microbe. 29(4):594-606.e6. PubMed
  57. Kaczanowska S, et al. 2021. Cell. 184(8):2033-2052.e21. PubMed
  58. Zasłona Z, et al. 2014. J Immunol. 193:4245. PubMed
  59. Kobayashi T, et al. 2019. Cell. 176:982. PubMed
  60. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  61. Fu B et al. 2017. Immunity. 47(6):1100-1113 . PubMed
  62. Chen L, et al. 2019. Cell Mol Gastroenterol Hepatol. 7:623. PubMed
  63. Kenichi Shimada et al. 2018. Immunity. 49(5):873-885 . PubMed
  64. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  65. Shen Y, et al. 2021. Comput Struct Biotechnol J. 19:5360. PubMed
  66. Súarez-López L, et al. 2021. iScience. 24:103406. PubMed
  67. Leach SM, et al. 2020. Cell Rep. 33:108337. PubMed
  68. Dong L, et al. 2021. Cancer Cell. . PubMed
  69. Amano C, et al. 2015. PLoS One. 10: 0137207. PubMed
  70. Sun P, et al. 2015. J Hepatol. . PubMed
  71. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  72. Yang X, et al. 2020. Blood Sci. 2:89. PubMed
  73. Castellanos CA, et al. 2021. Sci Immunol. 6:eabh0707. PubMed
  74. Tan X, et al. 2021. Front Oncol. 11:768222. PubMed
  75. Biswas S, et al. 2021. Nature. 591:464. PubMed
  76. Hirano KI, et al. 2021. eLife. 0.416666666666667. PubMed
  77. Yuan Q, et al. 2021. Cell Reports. 34(5):108724. PubMed
  78. Zheng H, et al. 2021. Frontiers in Cell and Developmental Biology. 9:641527. PubMed
  79. Khandelwal P, et al. 2013. PLoS One. 8:64193. PubMed
  80. Neubert K, et al. 2014. J Immunol. 192:5830. PubMed
  81. Galle E, et al. 2022. Genome Biol. 23:207. PubMed
  82. Cai B, et al. 2021. Mol Cancer. 20:165. PubMed
  83. Glaubitz J, et al. 2022. Nat Commun. 13:4502. PubMed
  84. Xiong A, et al. 2022. EBioMedicine. 83:104239. PubMed
  85. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  86. Zhu B, et al. 2021. Immunity. 54(6):1200-1218.e9. PubMed
  87. Pan H, et al. 2020. Mol Psychiatry. . PubMed
  88. Nguyen SL, et al. 2021. Sci Rep. 11:4217. PubMed
  89. Koh EH, et al. 2018. Diabetes. 67(12). PubMed
  90. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  91. Anastasiou M, et al. 2021. JCI Insight. 6:. PubMed
  92. Jiao H, et al. 2021. Cell. 184(11):2896-2910.e13. PubMed
  93. Lu S, et al. 2020. JCI Insight. 5:00. PubMed
  94. Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
  95. Plein A, et al. 2018. Nature. 562:223. PubMed
  96. Jeong SJ, et al. 2021. Autophagy. 17:3740. PubMed
  97. Montel-Hagen A, et al. 2020. Cell Rep. 33:108320. PubMed
  98. JI B, et al. 2016. Cell Death Differ. 23:759-75. PubMed
  99. Bunn P, et al. 2014. J Immunol. 192:3709. PubMed
  100. Nishi C, et al. 2014. Mol Cell Biol. 34:1512. PubMed
  101. Fulham MA, et al. 2019. Am J Physiol Cell Physiol. 317:C687. PubMed
  102. Gu H, et al. 2018. Aging (Albany NY). 1.525694444. PubMed
  103. Cong J et al. 2018. Cell metabolism. 28(2):243-255 . PubMed
  104. Xu G, et al. 2022. Cell Death Dis. 13:888. PubMed
  105. Raineri D, et al. 2021. Biomedicines. 10:. PubMed
  106. Park D, et al. 2020. Cancer Res. 80:4172. PubMed
  107. Bretscher P, et al. 2015. EMBO Mol Med. 7:593. PubMed
  108. Pereira JA, et al. 2020. Hum Mol Genet. 29:1253. PubMed
  109. Yue X, et al. 2019. Nat Commun. 10:2011. PubMed
  110. Yu Y, et al. 2022. Nat Commun. 13:6857. PubMed
  111. Wang J, et al. 2021. Nat Commun. 12:6198. PubMed
  112. Fennell LM, et al. 2020. EMBO J. 39:e103303. PubMed
  113. Guo P, et al. 2021. J Immunol. 207:408. PubMed
  114. Li W, et al. 2021. Front Pharmacol. 12:697483. PubMed
  115. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  116. Qi T, et al. 2020. Cell Rep. 33:108452. PubMed
  117. Bogie JF, et al. 2020. Ther Adv Chronic Dis. 11:2040622320947378. PubMed
  118. Nayak RR, et al. 2021. Cell Host Microbe. 29(3):362-377.e11. PubMed
  119. Zhang F, et al. 2020. EMBO Mol Med. e12034:12. PubMed
  120. Lu CY, et al. 2020. J Neurosci. 40:9602. PubMed
  121. Okamura T, et al. 2021. Front Immunol. 12:669629. PubMed
  122. Qian SJ, et al. 2021. Front Immunol. 12:711337. PubMed
  123. Sun L, et al. 2015. J Immunol. 194:4891. PubMed
  124. Mishra BB, et al. 2017. Nat Microbiol. 2:17072. PubMed
  125. Uribesalgo I, et al. 2019. EMBO Mol Med. 11:e9266. PubMed
  126. Wei W, et al. 2022. mSystems. 7:e0046922. PubMed
  127. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  128. Zuo W, et al. 2022. Cell Death Discov. 8:257. PubMed
  129. Xu M, et al. 2022. Genes Dis. 9:429. PubMed
  130. Xu Z, et al. 2020. Cancer Immunol Res. 1354:8. PubMed
  131. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  132. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  133. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  134. Lu S, et al. 2020. Arterioscler Thromb Vasc Biol. 40:394. PubMed
  135. Deczkowska A, et al. 2017. Nat Commun. 8:717. PubMed
  136. Chung L et al. 2018. Cell host & microbe. 23(2):203-214 . PubMed
  137. Sasaki T, et al. 2020. Cell Reports. 28(1):202-217.e7.. PubMed
  138. Dagher T, et al. 2021. J Exp Med. 218:. PubMed
  139. Anger-Góra N, et al. 2021. Oncol Lett. 22:582. PubMed
  140. Sharma A, et al. 2020. Cell. 183(2):377-394.e21. PubMed
  141. Liu Z, et al. 2021. Immunity. 54(2):247-258.e7. PubMed
  142. Huang Z, et al. 2021. Nat Commun. 12:145. PubMed
  143. Carbone C, et al. 2021. J Immunother Cancer. 9:. PubMed
  144. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  145. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  146. Lin W, et al. 2019. EBioMedicine. 49:133. PubMed
  147. Sendler M, et al. 2020. Gastroenterology. 158:253. PubMed
  148. Brown SM et al. 2017. Endocrinology. 158(10):3592-3604 . PubMed
  149. López MJ, et al. 2018. Invest Ophthalmol Vis Sci. 59:5671. PubMed
  150. Sydney Lavoie et al. 2019. eLife. 8 pii: e39982. PubMed
  151. Wu S, et al. 2022. BMC Immunol. 23:17. PubMed
  152. Rashid MH, et al. 2021. Oncol Rep. 45:1171. PubMed
  153. Zhao D, et al. 2020. Cancer Discov. 10:1374. PubMed
  154. Cruz-Herranz A, et al. 2021. JCI Insight. 6: . PubMed
  155. Covarrubias AJ, et al. 2020. Nat Metab. 1265:2. PubMed
  156. Stowe CL, et al. 2019. eLife. 0.333333333333333. PubMed
  157. Chatterjee D, et al. 2021. Cell Reports. 35(2):108996. PubMed
  158. Grauel AL, et al. 2020. Nat Commun. 4.84375. PubMed
  159. Carestia A, et al. 2019. Cell Rep. 28:896. PubMed
  160. Gubin MM, et al. 2018. Cell. 175:1014. PubMed
  161. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  162. Bhattacharya A, et al. 2018. Neuropsychopharmacology. 43:2586. PubMed
  163. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  164. Vachon L, et al. 2022. Theranostics. 12:1440. PubMed
  165. Ali S, et al. 2021. PLoS One. 16:e0246646. PubMed
  166. Bravo-Caparrós I, et al. 2020. FASEB J. 34:5951. PubMed
  167. Ni C, et al. 2021. Infect Immun. 89:. PubMed
  168. Pandit M, et al. 2021. Eur J Immunol. 51:1461. PubMed
  169. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  170. Hu Y, et al. 2021. Cell Death Dis. 12:743. PubMed
  171. Chruewkamlow N, et al. 2021. Stem Cell Res Ther. 12:520. PubMed
  172. Tozuka M, et al. 2016. J Dermatol Sci. 82: 38-45. PubMed
  173. Sharif O, et al. 2013. J Immunol. 190:5640. PubMed
  174. Dulken BW, et al. 2019. Nature. 571:205. PubMed
  175. Muri J, et al. 2020. eLife. 9:e53627.. PubMed
  176. Winchell CG, et al. 2020. Front Immunol. 1.077083333. PubMed
  177. Yu JM, et al. 2019. Nat Commun. 4.388888889. PubMed
  178. Hightower RM, et al. 2019. Mol Ther. 28:189. PubMed
  179. Xueyang Yu et al. 2017. Immunity. 47(5):903-912 . PubMed
  180. Bitschar K, et al. 2019. Nat Commun. 10:2730. PubMed
  181. Chen Z, et al. 2019. Mol Med Rep. 19:3210. PubMed
  182. Matsumura T, et al. 2022. Nat Commun. 13:7064. PubMed
  183. Hsu M, et al. 2022. Nat Immunol. 23:581. PubMed
  184. Sakamoto K, et al. 2021. Immunity. 54:2321. PubMed
  185. Raoof R, et al. 2021. J Neurosci. 41:8249. PubMed
  186. Guo D, et al. 2022. Bone Res. 10:45. PubMed
  187. Yousef H, et al. 2019. Nat Med. 25:988. PubMed
  188. Liu YG, et al. 2019. FASEB J. 33:5018. PubMed
  189. Bennett FC, et al. 2018. Neuron. 98:1170. PubMed
  190. Yang X, et al. 2018. Sci Rep. 8:188. PubMed
  191. Draijer C, et al. 2018. Sci Rep. 8:5105. PubMed
  192. Nagashima H et al. 2019. Immunity. 51(4):682-695 . PubMed
  193. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  194. Unsinger J, et al. 2021. J Leukoc Biol. 109:697. PubMed
  195. Da Mesquita S, et al. 2021. Science Advances. 7(21):. PubMed
  196. Chen M, et al. 2019. Cell Stem Cell. 25:501. PubMed
  197. Muri J, et al. 2020. Cell Reports. 29(9):2731-2744.e4.. PubMed
  198. Muchenditsi A, et al. 2017. Am J Physiol Gastrointest Liver Physiol. 313:G39. PubMed
  199. Tothova Z et al. 2017. Cell stem cell. 21(4):547-555 . PubMed
  200. Zhu K, et al. 2022. EMBO Rep. 23:e54499. PubMed
  201. Ding R, et al. 2022. J Neuroinflammation. 19:137. PubMed
  202. Xu JL, et al. 2022. Front Pharmacol. 13:911663. PubMed
  203. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  204. Hakim R, et al. 2021. J Neurosci. 41:8441. PubMed
  205. Gu H, et al. 2021. Elife. 10:. PubMed
  206. Kiss M, et al. 2020. Cancer Immunol Res. 9:309. PubMed
  207. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  208. Dallari S, et al. 2021. Cell Host Microbe. 29(6):1014-1029.e8. PubMed
  209. Lazarian G, et al. 2021. Cancer Cell. 39(3):380-393.e8. PubMed
  210. Rustenhoven J, et al. 2021. Cell. 184(4):1000-1016.e27. PubMed
  211. Liao Y, et al. 2020. Theranostics. 7.113888889. PubMed
  212. Montes de Oca M, et al. 2016. PLoS Pathog. 12: 1005398. PubMed
  213. Starr T, et al. 2018. PLoS One. 13:e0193601. PubMed
  214. Ding L et al. 2018. Cell reports. 25(11):2972-2980 . PubMed
  215. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  216. Meng Michelle Xu et al. 2017. Immunity. 47(2):363-373 . PubMed
  217. Jaitin DA et al. 2016. Cell. 167(7):1883-1896 . PubMed
  218. Zhang J, et al. 2018. Oncoimmunology. 7:e1461301. PubMed
  219. Hackstein CP, et al. 2022. Nat Commun. 13:7472. PubMed
  220. Chen J, et al. 2017. Sci Rep. 10.1038/s41598-017-00654-2. PubMed
  221. Danzer H, et al. 2020. Elife. 9:00. PubMed
  222. Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
  223. Stefan KL, et al. 2020. Cell. 1312:183. PubMed
  224. Molgora M, et al. 2020. Cell. 182:886. PubMed
  225. Werner A, et al. 2021. iScience. 24:103076. PubMed
  226. Baptista M, et al. 2016. Nat Commun. 7:12175. PubMed
  227. Guey B, et al. 2014. Proc Natl Acad Sci U S A. 111:17254. PubMed
  228. Ramanan D, et al. 2020. Cell. 181(6):1276-1290. PubMed
  229. Lee C, et al. 2020. Front Immunol. 11:77. PubMed
  230. Bohlen CJ et al. 2017. Neuron. 94(4):759-773 . PubMed
  231. Luo H, et al. 2019. Cell Rep. 26:945. PubMed
  232. Ishihara J, et al. 2018. Nat Commun. 9:2163. PubMed
  233. Peng V, et al. 2022. Nat Immunol. 23:619. PubMed
  234. Piirainen S, et al. 2021. Glia. 69:2459. PubMed
  235. Chen YL, et al. 2022. Front Neurosci. 16:876582. PubMed
  236. Sakamoto K, et al. 2022. STAR Protoc. 3:101052. PubMed
  237. Tummala G, et al. 2021. Invest Ophthalmol Vis Sci. 62:41. PubMed
  238. Maller O, et al. 2020. Nat Mater. 20:548. PubMed
  239. Maulhardt HA, et al. 2020. Invest New Drugs. 1618:38. PubMed
  240. McDonald MM, et al. 2021. Cell. 184(5):1330-1347.e13. PubMed
  241. Lee J, et al. 2015. Nat Commun. 6: 8499. PubMed
  242. Sen D, et al. 2016. PLoS One. 11:e0165064. PubMed
  243. Peltzer N, et al. 2018. Nature. 557:112. PubMed
  244. Koyama M et al. 2019. Immunity. 51(5):885-898 . PubMed
  245. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  246. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  247. Zhang M, et al. 2022. iScience. 25:104490. PubMed
  248. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  249. Liddelow S, et al. 2017. Nature. 541:481-487. PubMed
  250. Xu Z, et al. 2020. Cell Rep. 32:108041. PubMed
  251. Ang QY, et al. 2020. Cell. 181(6):1263-1275.e16. PubMed
  252. Zheng C, et al. 2021. J Extracell Vesicles. 10:e12109. PubMed
  253. Tripathi A, et al. 2021. Mol Psychiatry. 26:3043. PubMed
  254. Han J, et al. 2015. Cancer Res . 75: 5273 - 5282. PubMed
  255. Pessoa Rodrigues C, et al. 2020. Sci Adv. 6:eaaz4815. PubMed
  256. Strattan E, et al. 2020. Frontiers in Immunology. 2.131944444. PubMed
  257. Ribechini E, et al. 2017. Blood Adv. 0.699305556. PubMed
  258. Tan DQ, et al. 2019. Cell Rep. 26:2316. PubMed
  259. Tong Y, et al. 2018. EBioMedicine. 39:132. PubMed
  260. Aurélien Trompette et al. 2018. Immunity. 48(5):992-1005 . PubMed
  261. Chithanathan K, et al. 2022. Biology (Basel). 11:. PubMed
  262. Wang Y, et al. 2022. Nat Cell Biol. 24:230. PubMed
  263. Erens C, et al. 2022. Biomedicines. 10:. PubMed
  264. Yang F, et al. 2021. Nat Commun. 12:3424. PubMed
  265. Kapralov AA, et al. 2020. Nat Chem Biol. 278:16. PubMed
  266. Zheng H, et al. 2021. Frontiers in Immunology. 12:645100. PubMed
RRID
AB_893233 (BioLegend Cat. No. 101227)
AB_893232 (BioLegend Cat. No. 101228)

Antigen Details

Structure
Integrin family, associates with integrin β2 (CD18), 170 kD
Distribution

Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subsets of T and B cells

Function
Adhesion, chemotaxis
Ligand/Receptor
ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen
Cell Type
B cells, Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653.

Gene ID
16409 View all products for this Gene ID 3684 View all products for this Gene ID
UniProt
View information about CD11b on UniProt.org

Related FAQs

How stable is PerCP/Cyanine5.5 tandem as compared to PerCP alone?

PerCP/Cyanine5.5 is quite photostable and also better than PerCP alone in withstanding fixation.

Other Formats

View All CD11b Reagents Request Custom Conjugation
Description Clone Applications
PE/Cyanine7 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 750 anti-mouse/human CD11b M1/70 FC
TotalSeq™-A0014 anti-mouse/human CD11b M1/70 PG
Brilliant Violet 750™ anti-mouse/human CD11b M1/70 FC
TotalSeq™-B0014 anti-mouse/human CD11b M1/70 PG
TotalSeq™-C0014 anti-mouse/human CD11b M1/70 PG
Spark NIR™ 685 anti-mouse/human CD11b M1/70 FC
PE/Fire™ 640 anti-mouse/human CD11b M1/70 FC
APC anti-mouse/human CD11b M1/70 FC
Biotin anti-mouse/human CD11b M1/70 FC
FITC anti-mouse/human CD11b M1/70 FC
PE anti-mouse/human CD11b M1/70 FC,IHC
PE/Cyanine5 anti-mouse/human CD11b M1/70 FC
Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,IHC-F,ICC
Alexa Fluor® 488 anti-mouse/human CD11b M1/70 FC,IHC-F,3D IHC,SB
Alexa Fluor® 647 anti-mouse/human CD11b M1/70 FC,3D IHC,SB
Alexa Fluor® 700 anti-mouse/human CD11b M1/70 FC
Pacific Blue™ anti-mouse/human CD11b M1/70 FC
APC/Cyanine7 anti-mouse/human CD11b M1/70 FC
PerCP/Cyanine5.5 anti-mouse/human CD11b M1/70 FC
PerCP anti-mouse/human CD11b M1/70 FC
Brilliant Violet 421™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 570™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 605™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 650™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 711™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 785™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 510™ anti-mouse/human CD11b M1/70 FC,ICC
Ultra-LEAF™ Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,Block,Depletion,IHC-F,ICC
Purified anti-mouse/human CD11b (Maxpar® Ready) M1/70 FC,CyTOF®
Alexa Fluor® 594 anti-mouse/human CD11b M1/70 IHC-F,FC
PE/Dazzle™ 594 anti-mouse/human CD11b M1/70 FC
Spark YG™ 593 anti-mouse/human CD11b M1/70 FC
Spark YG™ 570 anti-mouse/human CD11b M1/70 IHC-F
PE/Fire™ 810 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 810 anti-mouse/human CD11b Antibody M1/70 FC
Spark Blue™ 550 anti-mouse/human CD11b M1/70 FC
Spark UV™ 387 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 806 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 780 anti-mouse/human CD11b M1/70 FC
Spark Blue™ 574 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
KIRAVIA Blue 520™ anti-mouse/human CD11b M1/70 FC
PE/Fire™ 744 anti-mouse/human CD11b M1/70 FC
Spark PLUS UV395™ anti-mouse/human CD11b M1/70 FC
Spark Red™ 718 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
Spark PLUS B550™ anti-mouse/human CD11b M1/70 FC
Spark YG™ 581 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
StarBright UltraViolet 575 anti-mouse/human CD11b M1/70 FC
StarBright UltraViolet 740 anti-mouse/human CD11b M1/70 FC
Spark PLUS V475™ anti-mouse/human CD11b M1/70 FC
Spark PLUS YG581™ anti-mouse/human CD11b M1/70 FC
Spark PLUS V450™ anti-mouse/human CD11b M1/70 FC
Go To Top Version: 2    Revision Date: 11/19/2018

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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