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Purified anti-mouse CD16/32 Antibody

Pricing & Availability
Clone
93 (See other available formats)
Regulatory Status
RUO
Other Names
Fcγ R III/II, Ly-17
Isotype
Rat IgG2a, λ
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Product Citations
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93_purified_051906
C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
  • 93_purified_051906
    C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
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101301 50 µg DKK214
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101302 500 µg DKK684
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Description

CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Sorted pre-B cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The CD16/32 antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IP, Block - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone 93 can be used for blocking of CD16/CD32 interactions with the Fc domain of immunoglobulins, but is not the same clone as 2.4G2.

The 93 mAb is specific to the common epitope of CD16/CD32. Additional reported applications (for the relevant formats) include: immunoprecipitation1 and blocking of Fc-mediated reactions in functional studies2,4,23. It is useful for blocking non-specific binding of immunoglobulin to Fc receptors. For blocking of Fc receptors in flow cytometric analysis, pre-incubate the cells with purified anti-CD16/CD32 antibody (=1.0 µg per 106 cells in 100 µL volume) for 5-10 minutes on ice prior to immunostaining. For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 101330) (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered).

Application References
  1. Personal communication (IP)
  2. Oliver AM, et al. 1999. Hybridoma 18:113. (Block)
  3. Brummel R and Lenert P. 2005. J. Immunol. 174:2429.
  4. Terrazas LI, et al. 2005. Int. J. Parasitol. 35:1349. (Block)
  5. Clements JL, et al. 2006. J. Immunol. 177:905.
  6. Mohamed W, et al. 2010. Infect Immun. 78:3306. PubMed
  7. Ouchi T, et al. 2011. J. Exp Med. 208:2607. PubMed
  8. Kmieciak M, et al. 2011. J. Vis. Exp. 47:2381. PubMed
  9. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  10. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  11. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  12. Koon HW, et al. 2013. J. Vis. Exp. 68:4208. PubMed
  13. Hegde VL, et al. 2013. J Biol Chem. 288:36810. PubMed
  14. Huang J, et al. 2013. J. Immunol Methods. 387:254. PubMed
  15. Dutow P, et al. 2014. J Infect Dis. PubMed
  16. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  17. Huang HN, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  18. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  19. Richardson ML, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  20. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  21. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  22. Everad A, et al. 2014. Nat Commun. 5:5648. PubMed
  23. Cenci E, et al. 2006. J. Leuko. Biol. 79(1):40-5. (Block)
Product Citations
  1. Lee J, et al. 2015. Hum Reprod. 10.1093/humrep/dev222. PubMed
  2. Jebbawi F, et al. 2021. Parasite Immunol. 43:e12834. PubMed
  3. Thomas R, et al. 2021. Immunology. 163:478. PubMed
  4. Herz J, et al. 2021. Neuron. 109:3609. PubMed
  5. Li H, et al. 2022. Cancer Cell. 40:36. PubMed
  6. Glynn RA, et al. 2022. J Immunol. 208:371. PubMed
  7. Kozuki S, et al. 2022. Genes Cells. 27:192. PubMed
  8. Bettke JA, et al. 2022. Infect Immun. 90:e0007022. PubMed
  9. Guttman O, et al. 2022. J Cell Biol. 221: . PubMed
  10. Miyao T, et al. 2022. Elife. 11: . PubMed
  11. Yin K, et al. 2022. Genes Dev. 36:533. PubMed
  12. Malhi H, et al. 2022. Cell Rep Med. 3:100658. PubMed
  13. Zhang Y, et al. 2022. Vaccines (Basel). 10: . PubMed
  14. Sugimoto S, et al. 2022. Nat Metab. 4:775. PubMed
  15. Hong Y, et al. 2022. J Leukoc Biol. 112:425. PubMed
  16. Que W, et al. 2022. Sci Adv. 8:eabo4413. PubMed
  17. Li X, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:1077. PubMed
  18. Akalu YT, et al. 2022. Elife. 11: . PubMed
  19. Zhang X, et al. 2022. EBioMedicine. 84:104275. PubMed
  20. Bottermann K, et al. 2022. Basic Res Cardiol. 117:48. PubMed
  21. Hao J, et al. 2022. Cell Rep. 41:111804. PubMed
  22. McNamara NB, et al. 2023. Nature. 613:120. PubMed
  23. Miró L, et al. 2022. Cancers (Basel). 14: . PubMed
  24. Liu P, et al. 2023. Clin Immunol. 246:109212. PubMed
  25. Ullah I, et al. 2023. Cell Rep Med. 4:100893. PubMed
  26. Al-Saafeen BH, et al. 2023. Front Immunol. 13:1017780. PubMed
  27. Cousin N, et al. 2022. Cells. 12: . PubMed
  28. Peng Q, et al. 2023. EMBO Rep. 24:e56034. PubMed
  29. Tichet M, et al. 2023. Immunity. 56:162. PubMed
  30. Zhou H, et al. 2023. Front Immunol. 13:1059687. PubMed
  31. Mandour MF, et al. 2023. Front Med (Lausanne). 9:1057252. PubMed
  32. Kemna J, et al. 2023. Nat Immunol. 24:414. PubMed
  33. Novaj A, et al. 2023. Int J Mol Sci. 24: . PubMed
  34. Ishikawa T, et al. 2023. Bio Protoc. 13:e4588. PubMed
  35. Liu X, et al. 2022. Pain. 163:508. PubMed
  36. Zhang M, et al. 2022. Mol Imaging Biol. 24:280. PubMed
  37. Zhang W, et al. 2022. Dev Cell. 57:329. PubMed
  38. Kodali S, et al. 2022. J Immunol. 208:1085. PubMed
  39. Chen K, et al. 2022. Adv Sci (Weinh). 9:e2104106. PubMed
  40. Zhang H, et al. 2022. Nat Cancer. 3:808. PubMed
  41. Fang Y, et al. 2022. Sci Immunol. 7:eabp9962. PubMed
  42. Koch MS, et al. 2022. Mol Ther Oncolytics. 26:275. PubMed
  43. Harapas CR, et al. 2022. Sci Immunol. 7:eabi4611. PubMed
  44. Ding P, et al. 2022. Elife. 11:. PubMed
  45. Deák P, et al. 2022. Cell Rep. 41:111563. PubMed
  46. Zhong J, et al. 2022. J Adv Res. 41:145. PubMed
  47. Melo-Silva CR, et al. 2022. Cell Rep. 41:111676. PubMed
  48. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  49. Wu Q, et al. 2023. Front Immunol. 13:1081719. PubMed
  50. Li L, et al. 2023. iScience. 26:106095. PubMed
  51. Torrente D, et al. 2023. J Neuroinflammation. 20:56. PubMed
  52. Bai X, et al. 2023. Nat Commun. 14:1247. PubMed
  53. Rocca Y, et al. 2023. Methods Mol Biol. 2618:187. PubMed
  54. Dang YZ, et al. 2023. Neoplasma. 70:123. PubMed
  55. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  56. Kudo T, et al. 2023. iScience. 26:106342. PubMed
  57. Liu KY, et al. 2023. Environ Health Perspect. 131:37014. PubMed
  58. Zhang YN, et al. 2023. Nat Commun. 14:1985. PubMed
  59. Iguchi A, et al. 2023. iScience. 26:106375. PubMed
  60. Feng Y, et al. 2023. J Transl Med. 21:290. PubMed
  61. Ji Y, et al. 2023. Nat Cell Biol. 25:726. PubMed
  62. Liu JC, et al. 2023. Int J Mol Sci. 24:. PubMed
  63. Petenkova A, et al. 2023. Nat Commun. 14:2761. PubMed
  64. Xu J, et al. 2023. Discov Oncol. 14:68. PubMed
  65. An R, et al. 2022. Cell Insight. 1:100047. PubMed
  66. Wang K, et al. 2023. Nat Commun. 14:2950. PubMed
  67. Amirova KM, et al. 2023. Int J Mol Sci. 24:. PubMed
  68. Li M, et al. 2023. BMC Cancer. 23:497. PubMed
  69. Mawambo G, et al. 2023. J Neuroinflammation. 20:145. PubMed
  70. Akasaka H, et al. 2023. JCI Insight. 8:. PubMed
  71. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  72. Filippini D, et al. 2019. Sci Rep. 9:12286. PubMed
  73. Flamar AL, et al. 2020. Immunity. 52(4):606-619.e6.. PubMed
  74. Sade-Feldman M,et al. 2017. Nat Commun.. 10.1038/s41467-017-01062-w. PubMed
  75. Michela Miani et al. 2018. Cell metabolism. 28(4):557-572 . PubMed
  76. Gan T, et al. 2019. Front Microbiol. 9:3174. PubMed
  77. Furuhashi K, et al. 2017. Immunology. 151:227. PubMed
  78. Fomin ME, et al. 2017. Cell Med. 0.45625. PubMed
  79. Bussières-Marmen S, et al. 2017. Cell Mol Immunol. 10.1038/cmi.2016.72. PubMed
  80. Chida J, et al. 2020. PLoS Pathog. 16:e1008823. PubMed
  81. Iyer S, et al. 2021. Cancer Discov. 0.725. PubMed
  82. Park E, et al. 2021. Journal of Neuroscience Research. . PubMed
  83. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  84. Kosti P, et al. 2021. Cell Reports Medicine. 2(4):100227. PubMed
  85. Barkaway A, et al. 2021. Immunity. . PubMed
  86. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  87. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  88. Foster A, et al. 2021. EBioMedicine. 71:103571. PubMed
  89. Kiepura A, et al. 2021. Int J Mol Sci. 22:. PubMed
  90. Rajagopalan A, et al. 2021. Cell Rep Methods. 1:. PubMed
  91. Guo H, et al. 2020. Curr Protoc Immunol. 131:e107. PubMed
  92. Van Braeckel-Budimir N, et al. 2021. J Immunother Cancer. 9:. PubMed
  93. Wang Z, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  94. Xiang G, et al. 2022. Cell Death Dis. 13:451. PubMed
  95. Nederlof R, et al. 2022. Front Immunol. 13:908023. PubMed
  96. Cerrato G, et al. 2021. Cell Death Differ. 28:1733. PubMed
  97. Da Mesquita S, et al. 2021. Nature. 593:255. PubMed
  98. Liu C, et al. 2022. Nat Nanotechnol. 17:531. PubMed
  99. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  100. Kitagawa S, et al. 2022. NPJ Vaccines. 7:115. PubMed
  101. Berry CT, et al. 2020. Cell Reports. 31(2):107474.. PubMed
  102. Rendeiro AF, et al. 2020. Nat Commun. 11:577. PubMed
  103. Biljes D, et al. 2017. EXCLI J. 0.86875. PubMed
  104. Zhang R, et al. 2019. Cell Rep. 28:2647. PubMed
  105. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  106. Zou B, et al. 2017. PLoS Pathogens. 13(6):e1006436. PubMed
  107. Rødahl I, et al. 2021. STAR Protoc. 2:100842. PubMed
  108. Correa S, et al. 2020. ACS Nano. 14:2224. PubMed
  109. Wong Fok Lung T, et al. 2020. Nat Microbiol. 141:5. PubMed
  110. Qian Y, et al. 2021. Cell Reports. 36(8):109602. PubMed
  111. Benitez AA, et al. 2020. Commun Biol. 0.371527778. PubMed
  112. Castoldi Â, et al. 2020. Nat Commun. 3.310416667. PubMed
  113. Mevel R, et al. 2020. eLife. 9:00. PubMed
  114. Golden GJ, et al. 2021. MBio. 12:e0118121. PubMed
  115. Yu Y, et al. 2022. iScience. 25:105004. PubMed
  116. Huang Y, et al. 2021. Nat Immunol. 22:586. PubMed
  117. MacLean M, et al. 2022. Commun Biol. 5:177. PubMed
  118. Effern M, et al. 2022. STAR Protoc. 3:101038. PubMed
  119. Weng L, et al. 2016. Sci Rep. 6:38632. PubMed
  120. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  121. Bhatia D, et al. 2019. JCI Insight. 4:e132826. PubMed
  122. Noh JR, et al. 2018. Sci Rep. 8:15222. PubMed
  123. Flores M, et al. 2008. FASEB J. 3.459027778. PubMed
  124. Tong J, et al. 2011. J Immunol. 186:3686. PubMed
  125. Tan H,et al. 2017. Mucosal Immunol. . 10.1038/mi.2017.89. PubMed
  126. Clarke F,et al. 2017. PLoS One. 10.1371/journal.pone.0186625. PubMed
  127. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  128. Minutti CM, et al. 2019. Immunity. 50:645. PubMed
  129. Farsakoglu Y et al. 2019. Cell reports. 26(9):2307-2315 . PubMed
  130. Takeda Y, et al. 2018. Innate Immun. 24:323. PubMed
  131. Goel S, et al. 2017. Nature. 548:471. PubMed
  132. Matsui S, et al. 2018. Am J Pathol. 188:2059. PubMed
  133. Browning D, et al. 2017. Gene Ther. 10.1038/gt.2016.88. PubMed
  134. Morris MG, et al. 2020. Comp Med. 70:336. PubMed
  135. Sano T, et al. 2021. Cell Reports. 36:109608. PubMed
  136. Martos-Rus C, et al. 2021. Sci Rep. 11:2974. PubMed
  137. Liu P, et al. 2021. Front Med (Lausanne). 8:625130. PubMed
  138. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  139. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  140. Khamissi FZ, et al. 2022. Sci Adv. 8:eabm5900. PubMed
  141. Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
  142. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  143. Feng J, et al. 2021. iScience. 24:103004. PubMed
  144. Wu L, et al. 2022. Front Immunol. 13:860761. PubMed
  145. Koon H, et al. 2012. J Vis Exp. 68: 4208. PubMed
  146. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  147. Diao L, et al. 2022. iScience. 25:105511. PubMed
  148. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  149. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  150. Hays C, et al. 2020. eLife. 8:e48772.. PubMed
  151. Li Y, et al. 2020. Cell Rep. 30:1753. PubMed
  152. Gawden‐Bone CM et al. 2018. Immunity. 49(3):427-437 . PubMed
  153. Tyagi AM et al. 2018. Immunity. 49(6):1116-1131 . PubMed
  154. Oyarce C, et al. 2018. Front Immunol. 8:1794. PubMed
  155. Liang F, et al. 2021. Front Immunol. 12:658715. PubMed
  156. Jenull S, et al. 2021. Cell Reports. 36(3):109406. PubMed
  157. Clark AL, et al. 2021. Diabetes Obesity and Metabolism. :. PubMed
  158. Stahnke S, et al. 2021. Current Biology. 31(10):2051-2064.e8. PubMed
  159. Yang SB, et al. 2021. Cancers (Basel). 13:00. PubMed
  160. Elisabeth Schrumpf, Xiaojun Jiang 2017. Physiol Rep. 10.14814/phy2.13117. PubMed
  161. Zhang Y, et al. 2022. Cancers (Basel). 14:. PubMed
  162. Mirshahi F, et al. 2022. Cell Rep. 38:110454. PubMed
  163. Sun SJ, et al. 2022. Commun Biol. 5:867. PubMed
  164. Chen X, et al. 2021. Cell Death Differ. 28:1237. PubMed
  165. Roberto Raúl SG, et al. 2022. Breast Cancer (Auckl). 16:11782234211065154. PubMed
  166. Matthias J, et al. 2020. J Clin Invest. 130:4587. PubMed
  167. Menzel L, et al. 2021. Cell Rep. 37:109878. PubMed
  168. Shen H, et al. 2022. Nat Commun. 13:6030. PubMed
  169. Carlson P, et al. 2019. Nat Cell Biol. 21:238. PubMed
  170. Wu J, et al. 2020. Sci Adv. 6:eaba3458. PubMed
  171. Guan H, et al. 2012. PLoS One. 7:e35650. PubMed
  172. Nakagawa S et al. 2017. Cell host & microbe. 22(5):667-677 . PubMed
  173. Mann M, et al. 2018. Cell Rep. 25:2992. PubMed
  174. Fiala GJ, et al. 2019. J Immunol. 203:569. PubMed
  175. Dave K et al. 2017. eLife. 6 pii: e23382. PubMed
  176. Kitashima DY, et al. 2018. EBioMedicine. 27:293. PubMed
  177. Li Y, et al. 2018. J Immunol. 201:2910. PubMed
  178. Hazama D, et al. 2020. Cell Chemical Biology. 27(9):1181-1191.e7. PubMed
  179. Shemer A, et al. 2020. Immunity. 53(5):1033-1049.e7. PubMed
  180. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  181. Okuniewska M, et al. 2021. Cell Reports. 36(2):109368. PubMed
  182. Zhao B, et al. 2021. Cell Reports. 36(3):109401. PubMed
  183. Webster HC, et al. 2020. J Immunol Methods. 112702:477. PubMed
  184. Godbersen-Palmer C, et al. 2020. J Immunol. 204:2973. PubMed
  185. Yang C, et al. 2020. J Control Release. 326:324. PubMed
  186. Liu D, et al. 2021. JCI Insight. 6:. PubMed
  187. Armaka M, et al. 2022. Genome Med. 14:78. PubMed
  188. Hoffman D, et al. 2021. Immunity. 54:2712. PubMed
  189. Terrazas LI, et al. 2005. Int J Parasit. 35:1349. PubMed
  190. Bhattacherjee A, et al. 2019. Commun Biol. 2:450. PubMed
  191. Lieschke S, et al. 2019. Cells. 0.420833333. PubMed
  192. Sereni L, et al. 2018. J Allergy Clin Immunol. 142:1272. PubMed
  193. Fransen F, et al. 2017. Front Immunol. 1.295138889. PubMed
  194. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  195. Wlodarska M et al. 2017. Cell host & microbe. 22(1):25-37 . PubMed
  196. Ma J, et al. 2021. Aging (Albany NY). 13:7211. PubMed
  197. Yu M, et al. 2021. J Clin Invest. 131:. PubMed
  198. Cousin N, et al. 2021. Cancer Res. 81:4133. PubMed
  199. Haugh KA, et al. 2021. eLife. 0.416666666666667. PubMed
  200. Tal MC, et al. 2020. MBio. 11:00. PubMed
  201. Zhang X, et al. 2020. J Immunol. 205:1743. PubMed
  202. Kovacs L, et al. 2020. PLoS One. 15:e0240455. PubMed
  203. Vackova J, et al. 2020. Int J Mol Sci. 21:00. PubMed
  204. Wang Y, et al. 2022. Front Immunol. 13:767630. PubMed
  205. Escudero-Lara A, et al. 2022. Front Behav Neurosci. 16:946975. PubMed
  206. Weiner AI, et al. 2019. NPJ Regen Med. 4:17. PubMed
  207. Russell SL, et al. 2019. Cell Rep. 29:3564. PubMed
  208. Khaw YM, et al. 2020. J Neuroinflammation. 17:49. PubMed
  209. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  210. Damle SR, et al. 2018. Allergy. 73:125. PubMed
  211. Wang L, et al. 2017. Front Immunol.. 10.3389/fimmu.2017.01754. PubMed
  212. Fiaturi N, et al. 2018. J Cell Commun Signal. 314:L127. PubMed
  213. Barajas‐Mora EM et al. 2018. Molecular cell. 73(1):48-60 . PubMed
  214. Fujita Y et al. 2018. Cell reports. 24(12):3296-3311 . PubMed
  215. Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
  216. Koliaraki V et al. 2019. Cell reports. 26(3):536-545 . PubMed
  217. Finn J et al. 2019. Cell reports. 26(11):2942-2954 . PubMed
  218. Barger SR, et al. 2019. Nat Commun. 10:1249. PubMed
  219. Shimokawa C et al. 2017. Immunity. 46(5):863-874 . PubMed
  220. Caronni N, et al. 2018. Cancer Res. 78:1685. PubMed
  221. Cheng XS, et al. 2020. J Cell Mol Med. 24:8391. PubMed
  222. Kohn M, et al. 2021. Front Immunol. 580594:12. PubMed
  223. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  224. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  225. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  226. Sheller-Miller S, et al. 2021. Sci Adv. 7:. PubMed
  227. Mao W, et al. 2021. Int J Mol Sci. 22:. PubMed
  228. Dang Y, et al. 2022. Cancer Cell Int. 22:88. PubMed
  229. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  230. Cong M, et al. 2021. Methods Mol Biol. 2388:59. PubMed
  231. Menzel L, et al. 2022. STAR Protoc. 3:101267. PubMed
  232. Gereke M, et al. 2012. J Vis Exp. 70: 4322. PubMed
  233. Lopez DA, et al. 2022. Cell Rep. 41:111677. PubMed
  234. MacConmara M, et al. 2011. J Leukoc Biol. 89:137. PubMed
  235. Cassidy LD, et al. 2018. Autophagy. 1.455555556. PubMed
  236. Fransen F, et al. 2017. Front Immunol. 8:154. PubMed
  237. Yang SH, et al. 2017. Front Immunol. 8:1192. PubMed
  238. Lagares D, et al. 2017. Sci Transl Med. 9:eaal3765. PubMed
  239. McLaughlin PA et al. 2019. PLoS Pathog. 15(7):e1007847 . PubMed
  240. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  241. Go MJ, et al. 2018. Mol Med Rep. 13:e0194423. PubMed
  242. McGrath-Morrow S, et al. 2017. Cytokine. 10.1016/j.cyto.2017.06.002. PubMed
  243. Korangath P, et al. 2020. Bio Protoc. 10:e3822. PubMed
  244. Flommersfeld S, et al. 2021. Immunity. :. PubMed
  245. Wong HS, et al. 2021. Cell. . PubMed
  246. Kusuyama J, et al. 2021. Cell Metabolism. 33(5):939-956.e8. PubMed
  247. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  248. Ruf B, et al. 2021. Cancer Immunol Res. 9:1024. PubMed
  249. Muñoz NM, et al. 2022. Sci Rep. 12:14449. PubMed
  250. Hu G, et al. 2022. Cell Death Dis. 13:640. PubMed
  251. Sun Y, et al. 2022. Nat Commun. 13:3916. PubMed
  252. Everard A, et al. 2014. Nat Commun. 5:5648. PubMed
  253. Francis M, et al. 2017. Toxicol Sci. 155(1):182-195. PubMed
  254. Deng M, et al. 2020. Nat Commun. 11:2193. PubMed
  255. Hashimoto M, et al. 2019. FASEB J. 33:8069. PubMed
  256. Csóka B, et al. 2018. JCI Insight. 38:200. PubMed
  257. Proto JD et al. 2018. Immunity. 49(4):666-677 . PubMed
  258. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
  259. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  260. Baasch S, et al. 2021. Cell. . PubMed
  261. Sutherland TE, et al. 2021. Frontiers in Immunology. 12:715209. PubMed
  262. Zheng J, et al. 2020. bioRxiv. . PubMed
  263. Imani J, et al. 2021. JCI Insight. 6:. PubMed
  264. Dang Y, et al. 2021. J Cancer. 12:7158. PubMed
  265. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  266. Pishesha N, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  267. Chin AL, et al. 2021. Nat Commun. 12:5138. PubMed
  268. Hong CH, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:925. PubMed
  269. Duvigneau S, et al. 2016. Sci Rep. 6:37045. PubMed
  270. Siggs O, et al. 2015. Proc Natl Acad Sci U S A. 112: E5706 - E5714. PubMed
  271. Lin C, et al. 2022. Nat Commun. 13:6869. PubMed
  272. Moon H, et al. 2020. Nat Commun. 4.270138889. PubMed
  273. Kulkarni U, et al. 2019. Mucosal Immunol. 12:545. PubMed
  274. Tsubaki T, et al. 2018. Oncotarget. 9:11209. PubMed
  275. Qi S et al. 2016. eLife. 5 pii: e14756. PubMed
  276. Roy K, et al. 2019. Immunity. 50:616. PubMed
  277. Baier FA, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:745. PubMed
  278. Li Y, et al. 2021. Sci Transl Med. 13:. PubMed
  279. Dobosz E, et al. 2021. Dis Model Mech. :14. PubMed
  280. Hubbard JJ, et al. 2020. J Exp Med. :217. PubMed
  281. Xu S, et al. 2021. Immunity. . PubMed
  282. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  283. Dieterich LC, et al. 2020. Angiogenesis. 1.24375. PubMed
  284. De Santi C, et al. 2022. Mol Ther Nucleic Acids. 29:643. PubMed
  285. Pereira M, et al. 2022. Cell Rep. 40:111225. PubMed
  286. Kim S, et al. 2022. Redox Biol. 54:102347. PubMed
  287. Chen Y, et al. 2022. Front Immunol. 13:835690. PubMed
  288. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  289. Welte T, et al. 2021. iScience. 24:103349. PubMed
  290. Dutow P, et al. 2014. J Infect Dis. 209:1269. PubMed
  291. Huang H, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  292. Jeong M, et al. 2022. JCI Insight. 7:. PubMed
  293. Peng L, et al. 2019. Mol Med Rep. 19:2876. PubMed
  294. Shin J, et al. 2018. Diabetes. 67:1068. PubMed
  295. Matsumoto K, et al. 2017. PLoS One. 12(6):e0175406. PubMed
  296. Sauma D, et al. 2017. Immunol Res. 10.1007/s12026-017-8936-9. PubMed
  297. Gil-Pulido J, et al. 2017. PLoS One.. 10.1371/journal.pone.0181947. PubMed
  298. Yu L, et al. 2019. Elife. 8:e46677. PubMed
  299. Chen JC, et al. 2018. Front Immunol. 0.665277778. PubMed
  300. Lehmann GL, et al. 2020. J Exp Med. 217:00:00. PubMed
  301. Zhao L, et al. 2020. EBioMedicine. 60:103020. PubMed
  302. Riedelberger M, et al. 2020. Bio Protoc. e3552:10. PubMed
  303. Yan W, et al. 2021. Front Med (Lausanne). 8:752223. PubMed
  304. Sun C, et al. 2022. J Adv Res. 35:71. PubMed
  305. Lüönd F, et al. 2022. STAR Protoc. 3:101438. PubMed
  306. Germundson DL, et al. 2022. Front Allergy. 3:870513. PubMed
  307. Sundararaj K, et al. 2021. Immunology. 162:418. PubMed
  308. Siggs O, et al. 2016. Proc Natl Acad Sci U S A. 113: 3706 - 3715. PubMed
  309. Seki T, et al. 2015. J Biochem. 158: 485 - 495. PubMed
  310. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  311. Hegde V, et al. 2013. J Biol Chem. 288:36810. PubMed
  312. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  313. Liu C et al. 2019. Immunity. 51(2):381-397 . PubMed
  314. Hu CF, et al. 2021. Front Immunol. 12:638381. PubMed
  315. Zheng J, et al. 2020. Nature. . PubMed
  316. Unudurthi SD, et al. 2020. Life Sci. 117440:247. PubMed
  317. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  318. Troutman TD, et al. 2021. STAR Protocols. 2(1):100363. PubMed
  319. Li X, et al. 2020. Nat Commun. 4.877777778. PubMed
  320. Chu A, et al. 2021. J Reprod Immunol. 145:103309. PubMed
  321. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  322. Moon S, et al. 2021. J Exp Med. 218:. PubMed
  323. Kmieciak M, et al. 2011. J Vis Exp. 47: 2381. PubMed
  324. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  325. Kretschmer L, et al. 2020. Nat Commun. 0.536805556. PubMed
  326. Fujimoto N, et al. 2020. PLoS Biol. 18:e3000704. PubMed
  327. Akk A, et al. 2019. Mol Immunol. 114:629. PubMed
  328. Enomoto D, et al. 2017. PLoS One.. 10.1371/journal.pone.0183584. PubMed
  329. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  330. Zeng J, et al. 2018. J Immunol. 200:3407. PubMed
  331. Hsu BE et al. 2019. Cell Rep. 27(13):3902-3915 . PubMed
  332. Di Mitri D, et al. 2019. Cell Rep. 28:2156. PubMed
  333. Rebecca S Dickinson et al. 2017. Wellcome open research. 0.155555556 . PubMed
  334. Li B, et al. 2019. Oncol Rep. 41:608. PubMed
  335. Huang BR, et al. 2020. Int J Mol Sci. 21:00. PubMed
  336. Lindborg JA, et al. 2021. Cell Reports. 34(9):108777. PubMed
  337. Ahn D, et al. 2021. Cell Reports. 35(9):109196. PubMed
  338. Tuong ZK, et al. 2021. iScience. 24:103326. PubMed
  339. Yu H, et al. 2021. Front Oncol. 11:736882. PubMed
  340. Shiozawa S, et al. 2022. iScience. 25:103537. PubMed
  341. Blanchard L, et al. 2022. STAR Protoc. 3:101444. PubMed
  342. Babagana M, et al. 2021. Aging (Albany NY). 13:19207. PubMed
  343. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  344. Matsuda T, et al. 2022. iScience. 25:105324. PubMed
  345. Constantinides M, et al. 2011. J Immunol. 187:309. PubMed
  346. Lenert R 2005. J Immunol. 174:2429. PubMed
  347. Ramachandran P, et al. 2019. Nature. 575:512. PubMed
  348. Spranger S, et al. 2017. Cancer Cell. 31:711. PubMed
  349. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  350. Sanchez M et al. 2017. Cell host & microbe. 22(4):543-551 . PubMed
  351. Shibamoto M, et al. 2019. Int Heart J. 60:944. PubMed
  352. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  353. Mohammadi MR, et al. 2021. Commun Biol. 4:685. PubMed
  354. Vilcaes AA, et al. 2020. Int J Mol Sci. :21. PubMed
  355. Zhao L, et al. 2021. STAR Protocols. 2:100732. PubMed
  356. Desai P, et al. 2021. Cell. 184(5):1214-1231.e16. PubMed
  357. Lehmann ML, et al. 2020. Brain Behav Immun. 88:735. PubMed
  358. Xu G, et al. 2020. Cell Rep. 32:108170. PubMed
  359. Takahashi F, et al. 2022. iScience. 25:104278. PubMed
  360. Saveljeva S, et al. 2022. Cell Metab. 34:106. PubMed
  361. Zhang YN, et al. 2021. Sci Adv. 7:eabj3107. PubMed
  362. Shibuya M, et al. 2021. iScience. 24:103131. PubMed
  363. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  364. López-Sanz C, et al. 2022. STAR Protoc. 3:101755. PubMed
  365. Lyle C, et al. 2019. Sci Rep. 9:20257. PubMed
  366. Roussey JA, et al. 2017. J Immunol. 199:3535. PubMed
  367. Mandour MF, et al. 2020. Infect Agent Cancer. 15:30. PubMed
  368. Kolter J, et al. 2020. Immunity. 50(6):1482-1497. PubMed
  369. Nakav S, et al. 2009. Nephrol Dial Transplant. 25:931. PubMed
  370. Miranda-Hernandez S, et al. 2011. J Immunol. 187:791. PubMed
  371. Okuma A, et al. 2017. Nat Commun.. 10.1038/s41467-017-02281-x. PubMed
  372. Kang YH, et al. 2019. Nat Commun. 10:912. PubMed
  373. Tellechea M, et al. 2018. J Immunol. 200:305. PubMed
  374. Oliveira AC et al. 2017. eLife. 6 pii: e30883. PubMed
  375. Miura N, et al. 2017. Mol Ther. 10.1016/j.ymthe.2017.01.020. PubMed
  376. Liu P, et al. 2020. Mol Cell. 748:77. PubMed
  377. Zhang Y, et al. 2020. Cancer Res. 80:3345. PubMed
  378. Bi J, et al. 2022. Front Microbiol. 13:927122. PubMed
  379. Zhang MH, et al. 2020. Front Immunol. 11:560. PubMed
  380. Ouchi T, et al. 2011. J Exp Med. 208:2607. PubMed
  381. Baumann D, et al. 2020. Nat Commun. 1.969444444. PubMed
  382. Forster R, et al. 2019. FASEB J. 33:11210. PubMed
  383. Heinen A, et al. 2019. Mol Ther. 27:46:00. PubMed
  384. Simmons S et al. 2019. Elife. 8 pii: e41239. PubMed
  385. William M, et al. 2018. J Immunol. 200:4102. PubMed
  386. Contreras NA, et al. 2019. PLoS Pathog. 15:e1007890. PubMed
  387. Miura Y et al. 2018. eLife. 7 pii: e36572. PubMed
  388. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  389. Chida K, et al. 2021. Biol Pharm Bull. 44:1551. PubMed
  390. Saxena M, et al. 2020. Cancer Res. 80:3631. PubMed
  391. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  392. Alshetaiwi H, et al. 2020. Methods Mol Biol. 2236:177. PubMed
  393. Ma L, et al. 2022. Sci Adv. 8:eabm3470. PubMed
  394. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  395. Lee SA, et al. 2021. Cells. 10:. PubMed
  396. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  397. Howe C, et al. 2016. Sci Rep. 6:28699. PubMed
  398. Schaftenaar FH, et al. 2019. Sci Rep. 9:17391. PubMed
  399. Deng M, et al. 2019. J Exp Med. 216:2838. PubMed
  400. Hong JP, et al. 2020. Cell Reports Medicine. 1(3):100035. PubMed
  401. Clements J, et al. 2006. J Immunol. 177:905. PubMed
  402. Gaya M et al. 2018. Cell. 172(3):517-533 . PubMed
  403. Freeman SA et al. 2018. Cell. 172(1-2):305-317 . PubMed
  404. Glodde N et al. 2017. Immunity. 47(4):789-802 . PubMed
  405. Knox T, et al. 2019. Sci Rep. 9:6136. PubMed
  406. Rojo R, et al. 2019. Nat Commun. 10:3215. PubMed
  407. Blaszczak AM, et al. 2020. Immunometabolism. 2:00. PubMed
  408. Senatus L, et al. 2020. JCI Insight. 5:00. PubMed
  409. Matsumoto M, et al. 2021. Cell Host Microbe. 29(6):930-940.e4. PubMed
  410. Jin HS, et al. 2020. Cancer Immunol Res. 8:912. PubMed
  411. Sakurai Y, et al. 2021. Pharmaceutics. 13:. PubMed
  412. Banskota S, et al. 2021. Inflamm Bowel Dis. 27:914. PubMed
  413. Magaletta ME, et al. 2022. Nat Commun. 13:457. PubMed
  414. Tzeng TT, et al. 2022. NPJ Vaccines. 7:60. PubMed
  415. Kim K, et al. 2015. Infect Immun . 83:1150. PubMed
  416. Chryplewicz A, et al. 2022. Cancer Cell. 40:1111. PubMed
  417. Penzo M, et al. 2010. J Immunol. 184:4497. PubMed
  418. Mehrpouya-Bahrami P, et al. 2019. J Biol Chem. 294:7669. PubMed
  419. Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
  420. Blaszczak AM, et al. 2019. J Immunol. 202:2451. PubMed
  421. Sivaram N, et al. 2019. J Clin Invest. 130. PubMed
  422. Litwinoff EMS, et al. 2017. Obes Res Clin Pract. 12:174. PubMed
  423. Burl RB et al. 2018. Cell metabolism. 28(2):300-309 . PubMed
  424. Chetty A, et al. 2021. Cell Host Microbe. 29:579. PubMed
  425. Qiu Z, et al. 2020. Cancer Genet. 245:6. PubMed
  426. Kohn M, et al. 2021. Front Immunol. 626627:12. PubMed
  427. Bonavita E, et al. 2020. Immunity. 1215:53. PubMed
  428. Luo X, et al. 2021. Neuron. 109:2691. PubMed
  429. McDonald MM, et al. 2021. Cell. 184(5):1330-1347.e13. PubMed
  430. Alam MM, et al. 2021. eneuro. 8(1):. PubMed
  431. Sitapara RA, et al. 2020. Mol Med. 26:63. PubMed
  432. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  433. Dong H, et al. 2022. Nat Metab. 4:90. PubMed
  434. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  435. Melero I, et al. 2015. Cancer Res. 75:497. PubMed
  436. Hegde V, et al. 2015. J Immunol. 194:5211. PubMed
  437. Steinmann S, et al. 2020. Sci Rep. 1.160416667. PubMed
  438. Li Z et al. 2018. Immunity. 49(4):640-653 . PubMed
  439. Lyons DO, et al. 2018. PLoS One. 13:e0207704. PubMed
  440. Li A, et al. 2018. Cancer Lett. 431:54. PubMed
  441. Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed
  442. Goldberg EL, et al. 2021. Cell Metabolism. :. PubMed
  443. Phadke MS, et al. 2021. Cancer Immunol Res. 9:554. PubMed
  444. Sibler E, et al. 2021. Cells. 10:. PubMed
  445. Qin J, et al. 2020. Cancer Immunol Res. 8:1426. PubMed
  446. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  447. Zhang M, et al. 2022. iScience. 25:104490. PubMed
  448. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  449. Sibler E, et al. 2022. Cancers (Basel). 14:. PubMed
  450. Liu Q, et al. 2016. Cell Death Dis. 1.93125. PubMed
  451. Richardson M, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  452. Huanga J, et al. 2013. J Immunol Methods. 387:254. PubMed
  453. Malinczak CA, et al. 2019. J Immunol. 10.4049/jimmunol.1900741. PubMed
  454. Wang X, et al. 2018. Front Immunol. 9:2615. PubMed
  455. Kabir AU, et al. 2018. JCI Insight. 3. PubMed
  456. Buschor S, et al. 2017. PLoS Pathogens. 13(6):e1006476. PubMed
  457. Effern M, et al. 2020. Immunity. 53(3):564-580.e9. PubMed
RRID
AB_312800 (BioLegend Cat. No. 101301)
AB_312801 (BioLegend Cat. No. 101302)

Antigen Details

Structure
Ig superfamily, 40-60 kD
Distribution

B cells, monocyte/macrophages, NK cells, neutrophils, mast cells, dendritic cells

Function
Low affinity receptors for IgG
Ligand/Receptor
IgG
Cell Type
B cells, Dendritic cells, Macrophages, Mast cells, Monocytes, Neutrophils, NK cells
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules, Fc Receptors
Antigen References

1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Unkeless JC. 1989. J. Clin. Invest. 83:355.
3. Qiu WQ, et al. 1990. Science 248:732.

Gene ID
14130 View all products for this Gene ID 14131 View all products for this Gene ID
UniProt
View information about CD16/32 on UniProt.org

Related FAQs

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Go To Top Version: 2    Revision Date: 01/23/2015

For Research Use Only. Not for diagnostic or therapeutic use.

 

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