Loading...

APC anti-mouse/human CD11b Antibody

Pricing & Availability
Clone
M1/70 (See other available formats)
Regulatory Status
RUO
Other Names
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
M1slash70_APC_042706
C57BL/6 mouse bone marrow cells were stained with CD11b (clone M1/70) APC (filled histogram) or rat IgG2b, κ APC isotype control (open histogram) (gated on total cells).
  • M1slash70_APC_042706
    C57BL/6 mouse bone marrow cells were stained with CD11b (clone M1/70) APC (filled histogram) or rat IgG2b, κ APC isotype control (open histogram) (gated on total cells).
Compare all formats See APC spectral data
Cat # Size Price Quantity Check Availability Save
101211 25 µg DKK197
Check Availability


Need larger quantities of this item?
Request Bulk Quote
101212 100 µg DKK624
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human, Cynomolgus, Rhesus
Reported Reactivity
Chimpanzee, Baboon, Rabbit
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
C57BL/10 splenocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The CD11b antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F).

Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1,4, in vitro blocking3,9,12, depletion2,8, immunofluorescence microscopy6,7,10, immunohistochemistry of acetone-fixed frozen sections5,11-13, and spatial biology (IBEX)35,36. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).

Application References
  1. Springer T, et al. 1978. Eur. J. Immunol. 8:539. (IP)
  2. Ault K and Springer T. 1981. J. Immunol. 126:359. (Deplete)
  3. Springer TA, et al. 1982. Immunol. Rev. 68:171. (Block)
  4. Ho MK and Springer TA. 1983. J. Biol. Chem. 258:2766. (IP)
  5. Flotte TJ, et al. 1983. Am. J. Pathol. 111:112. (IHC)
  6. Noel GJ, et al. 1990. J. Clin. Invest. 85:208. (IF)
  7. Allen LA and Aderem A. 1996. J. Exp. Med. 184:627 (IF)
  8. D'Amico A and Wu L. 2003. J. Exp. Med. 198:293. (Deplete)
  9. Brickson SJ, et al. 2003. Appl Physiol. 95:969. (Block)
  10. Clatworthy MR and Smith KG. 2004. J. Exp. Med. 199:717. (IF)
  11. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  12. Zhang Y, et al. 2002. J. Immunol. 168:3088. (IHC)
  13. Iwasaki A and Kelsall BL. 2001. J. Immunol. 166:4884 (IHC, FC)
  14. Tailleux L. 2003. J. Exp. Med. 197:121. (Block, FC)
  15. Olver S, et al. 2006. Cancer Research 66:571. (FC)
  16. Tan SL, et al. 2006. J. Immunol. 176:2872. (FC) PubMed
  17. Ponomarev ED, et al. 2006. J. Immunol. 176:1402. (FC)
  18. Dzhagalov I, et al. 2007. Blood 109:1620. (FC)
  19. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  20. Rasmussen JW, et al. 2006. Infect. Immun.74:6590. PubMed
  21. Napimoga MH, et al. 2008. J. Immunol. 180:609. PubMed
  22. Elqaraz-Carmon V, et al. 2008. J. Lipid. Res. 49:1894. PubMed
  23. Kim DD, et al. 2008. Blood 112:1109. PubMed
  24. Guo Y, et al. 2008. Blood 112:480. PubMed
  25. Norian LA, et al. 2009. Cancer Res. 69:3086. (FC) PubMed
  26. Baumgartner CK, et al. 2010. J. Immunol. 184:573. PubMed
  27. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  28. Whiteland J, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
  29. Weber GF, et al. 2014. J Exp Med. 211:1243. PubMed
  30. Ashok A, et al. 2015. Toxicol Sci. 143:64. PubMed
  31. Price PJ, et al. 2015. J Immunol. 194:1164. PubMed
  32. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  33. Ferreira R, et al. 2016. J Infect Dis. 213: 669 - 673. PubMed
  34. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  35. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  36. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Chang YS, et al. 2020. Int J Mol Sci. 21:00. PubMed
  2. Chen Q, et al. 2019. Cell Stem Cell. 25(6):768-783.e6. PubMed
  3. Sun L, et al. 2021. Cancer Cell. 39:1361. PubMed
  4. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  5. Chuang H, et al. 2014. Nat Commun. 5:4602. PubMed
  6. Guo H, Cooper S, Friedman A, et al. 2017. PLoS One. 10.1371/journal.pone.0150809. PubMed
  7. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  8. Jiang W, et al. 2017. Sci Rep. 7:6501. PubMed
  9. Schröder N, et al. 2020. J Neuroinflammation. 17:131. PubMed
  10. Frieler RA, et al. 2017. Exp Neurol. 298:104. PubMed
  11. Combes F, et al. 2018. Neoplasia. 20:848. PubMed
  12. Lin C et al. 2019. Immunity. 50(1):137-151 . PubMed
  13. Bruno MEC, et al. 2022. J Cell Physiol. 237:706. PubMed
  14. Friesen M, et al. 2022. Brain Pathol. 32:e13032. PubMed
  15. Zhang C, et al. 2022. Genomics Proteomics Bioinformatics. :. PubMed
  16. Liang X, et al. 2022. Cancer Commun (Lond). 42:205. PubMed
  17. Gadipudi LL, et al. 2022. Clin Sci (Lond). 136:643. PubMed
  18. Guttman O, et al. 2022. J Cell Biol. 221: . PubMed
  19. Van Deren DA, et al. 2022. Development. 149: . PubMed
  20. Lu R, et al. 2022. Scand J Immunol. 96:e13177. PubMed
  21. Liu X, et al. 2022. Adv Sci (Weinh). 9:e2105650. PubMed
  22. Tsumita T, et al. 2022. Int J Cancer. 151:944. PubMed
  23. Li F, et al. 2022. Gut Microbes. 14:2096989. PubMed
  24. Liu X, et al. 2022. Chin Med J (Engl). 135:1821. PubMed
  25. Li X, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:1077. PubMed
  26. Wu X, et al. 2022. J Clin Med. 11: . PubMed
  27. Zhang Z, et al. 2022. Mol Nutr Food Res. 66:e2200300. PubMed
  28. Li GX, et al. 2022. Int J Biochem Cell Biol. 152:106299. PubMed
  29. Wohlgemuth L, et al. 2022. Cells. 11: . PubMed
  30. Millar FR, et al. 2022. Cell Rep. 41:111596. PubMed
  31. Liu M, et al. 2022. Cells. 11: . PubMed
  32. Zhu J, et al. 2022. Nat Commun. 13:7466. PubMed
  33. Cai S, et al. 2023. J Clin Invest. 133: . PubMed
  34. Lee DE, et al. 2022. Nat Commun. 13:7613. PubMed
  35. Cheng P, et al. 2023. Pharmacol Res. 188:106643. PubMed
  36. Domingos-Pereira S, et al. 2022. Int J Mol Sci. 24: . PubMed
  37. Cagle LA, et al. 2023. Front Physiol. 13:1059686. PubMed
  38. Jin SM, et al. 2023. Nat Nanotechnol. :. PubMed
  39. Zhang L, et al. 2023. J Inflamm Res. 16:109. PubMed
  40. Olivares-González L, et al. 2022. Antioxidants (Basel). 12: . PubMed
  41. Peng Y, et al. 2023. Respir Res. 24:33. PubMed
  42. Wang C, et al. 2023. Exp Mol Med. 55:347. PubMed
  43. Schwartz M, et al. 2023. Nat Microbiol. 8:455. PubMed
  44. Tsioti I, et al. 2023. J Neuroinflammation. 20:25. PubMed
  45. Hattori Y, et al. 2023. Cell Rep. 42:112092. PubMed
  46. Chen Y, et al. 2023. Stem Cells Int. 2023:7482546. PubMed
  47. Lu QK, et al. 2022. Acta Pharmacol Sin. 43:376. PubMed
  48. Liu X, et al. 2022. Pain. 163:508. PubMed
  49. Ryan CB, et al. 2022. Neurobiol Dis. 163:105608. PubMed
  50. Sohn J, et al. 2022. Blood Adv. 6:2557. PubMed
  51. Howard ZM, et al. 2022. Am J Physiol Cell Physiol. 322:C354. PubMed
  52. Ma Y, et al. 2022. Am J Physiol Heart Circ Physiol. 322:H622. PubMed
  53. Leick MB, et al. 2022. Cancer Cell. 40:494. PubMed
  54. Pulous FE, et al. 2022. Nat Neurosci. 25:567. PubMed
  55. Pfeifhofer-Obermair C, et al. 2022. Bio Protoc. 12:e4378. PubMed
  56. Awida Z, et al. 2022. Int J Mol Sci. 23:. PubMed
  57. Abdel-Haq R, et al. 2022. Elife. 11:. PubMed
  58. Zhang Y, et al. 2023. Invest Ophthalmol Vis Sci. 64:1. PubMed
  59. Zhao Q, et al. 2023. Signal Transduct Target Ther. 8:40. PubMed
  60. Zhang X, et al. 2023. Heliyon. 9:e13490. PubMed
  61. Zhong WJ, et al. 2023. J Transl Med. 21:179. PubMed
  62. Ma X, et al. 2023. Nat Commun. 14:1606. PubMed
  63. Zhuang WR, et al. 2023. Nat Commun. 14:1675. PubMed
  64. Rundberg Nilsson A, et al. 2023. iScience. 26:106341. PubMed
  65. Palakurthi B, et al. 2023. Nat Commun. 14:2109. PubMed
  66. Silva BM, et al. 2023. J Clin Invest. 133:. PubMed
  67. Duan JL, et al. 2023. Nat Aging. 3:258. PubMed
  68. Li T, et al. 2023. Nat Commun. 14:2498. PubMed
  69. Yu PC, et al. 2023. Pharmaceuticals (Basel). 16:. PubMed
  70. Arora S, et al. 2023. PLoS One. 18:e0286211. PubMed
  71. Kase N, et al. 2023. Front Cell Dev Biol. 11:1022081. PubMed
  72. Tsugawa H, et al. 2023. PLoS Pathog. 19:e1011139. PubMed
  73. Fixsen BR, et al. 2023. Nat Immunol. . PubMed
  74. Bruggemann TR, et al. 2022. iScience. 25:105185. PubMed
  75. Lawson H, et al. 2021. Stem Cell Reports. 16:2784. PubMed
  76. Kuo PC, et al. 2021. Brain Commun. 3:fcab187. PubMed
  77. Li F, et al. 2022. Mediators Inflamm. 2022:5782922. PubMed
  78. Hao Y, et al. 2022. Exp Ther Med. 23:350. PubMed
  79. Yang D, et al. 2022. Cell. 185:1905. PubMed
  80. Kataru RP, et al. 2021. Sci Signal. 14:. PubMed
  81. Huck NA, et al. 2021. J Neurosci. 41:4349. PubMed
  82. Tang L, et al. 2021. Oncol Lett. 22:605. PubMed
  83. Almada AE, et al. 2021. Cell Reports. 34(4):108656. PubMed
  84. Kokona D, et al. 2016. Exp Eye Res. S0014-4835(16)30499-7. PubMed
  85. Oliveira-Lima OC, et al. 2015. Immunobiology. . PubMed
  86. Viny AD, et al. 2019. Cell Stem Cell. 25:682. PubMed
  87. Paris J et al. 2019. Cell Stem Cell. 25(1):137-148 . PubMed
  88. Page N, et al. 2018. Immunity. 48:937. PubMed
  89. Frisbee AL, et al. 2019. Nat Commun. 10:2712. PubMed
  90. Sanders KA, et al. 2019. Sci Rep. 9:231. PubMed
  91. Hirata Y et al. 2018. Cell stem cell. 22(3):445-453 . PubMed
  92. Wang F, et al. 2018. Oncogenesis. 7:41. PubMed
  93. Schloss MJ, et al. 2022. Nat Immunol. 23:605. PubMed
  94. Tripathi H, et al. 2020. J Mol Cell Cardiol. 149:95. PubMed
  95. d'Errico P, et al. 2021. Nat Neurosci. Online ahead of print. PubMed
  96. Chen CC, et al. 2020. Cancer Cell. 37:71. PubMed
  97. Hanhai Z, et al. 2021. Aging (Albany NY). 13:13108. PubMed
  98. Zasłona Z, et al. 2014. J Immunol. 193:4245. PubMed
  99. Clark K, et al. 2015. J Autoimmun. Available online 21 August 2015. PubMed
  100. O’Dea K, et al. 2016. PLoS One. 11:e0167801. PubMed
  101. Ebneter A, et al. 2017. Transl Vis Sci Technol. 10.1167/tvst.6.2.10. PubMed
  102. Chen Y, et al. 2018. EBioMedicine. 32:31. PubMed
  103. Misumi I et al. 2019. Cell Rep. 27(5):1387-1396 . PubMed
  104. Song C, et al. 2019. Nat Commun. 10:3745. PubMed
  105. Saleh MM, et al. 2019. Cell Host Microbe. 25:756. PubMed
  106. Skinner DD, et al. 2022. Front Immunol. 13:931388. PubMed
  107. Zhang J, et al. 2021. MedComm (Beijing). 2:256. PubMed
  108. Hewitson JP, et al. 2020. J Immunol. 204:2949. PubMed
  109. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  110. Boldison J, et al. 2020. Cell Mol Immunol. 17:843. PubMed
  111. de Groot AE, et al. 2021. Prostate. 81:629. PubMed
  112. Rossi DC, et al. 2021. J Clin Invest. 131:. PubMed
  113. Pack AD, et al. 2021. Cell Reports. 36:109586. PubMed
  114. Larouche JA, et al. 2021. eLife. 0.416666666666667. PubMed
  115. Yousif AS, et al. 2020. Immunity. 54(2):235-246.e5. PubMed
  116. Elbaz M, et al. 2015. Mol Oncol. 9: 906-919. PubMed
  117. Yang Y, et al. 2020. Cell Death Discov. 0.293055556. PubMed
  118. Lutzmann M, et al. 2019. Cell Rep. 28:2851. PubMed
  119. Chow MT et al. 2019. Immunity. 50(6):1498-1512 . PubMed
  120. Chattopadhyay A, et al. 2018. Sci Rep. 8:9032. PubMed
  121. Mirshahi F, et al. 2022. Cell Rep. 38:110454. PubMed
  122. Oh DS, et al. 2021. Autophagy. 17:2111. PubMed
  123. Wang Q, et al. 2020. Wound Repair Regen. 28:105. PubMed
  124. Jia G, et al. 2022. Front Cell Dev Biol. 9:796757. PubMed
  125. Rogic A, et al. 2021. Nat Commun. 12:6889. PubMed
  126. Seita Y, et al. 2020. J Alzheimers Dis. 75:45:00. PubMed
  127. Shi L, et al. 2021. Immunity. . PubMed
  128. Go DM, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:715. PubMed
  129. Castiglioni A, et al. 2015. PLoS One. 10:128094. PubMed
  130. Nasser MW, et al. 2015. Cancer Res . 75: 974-985. PubMed
  131. Liu Y, et al. 2015. Sci Rep. 5:17215. PubMed
  132. Peng J, et al. 2016. Nat Commun. 7:12029. PubMed
  133. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  134. Yamashiro LH, et al. 2020. Nat Commun. 2.806944444. PubMed
  135. Fukushima T, et al. 2019. Cell Rep. 29:4144. PubMed
  136. Jin X, et al. 2019. Mol Cell. 73:22:00. PubMed
  137. Bae SH, et al. 2021. Theranostics. 11:2522. PubMed
  138. Mathur S, et al. 2021. JCI Insight. 6:. PubMed
  139. Kummer MP, et al. 2021. EMBO J. 40:e108662. PubMed
  140. Casali P, et al. 2021. Front Immunol. 12:761450. PubMed
  141. Xu M, et al. 2021. Front Physiol. 12:700338. PubMed
  142. Bell BJ, et al. 2022. Brain Behav Immun Health. 23:100478. PubMed
  143. Dolgova EV, et al. 2022. Int J Mol Sci. 23:. PubMed
  144. Xiong A, et al. 2022. EBioMedicine. 83:104239. PubMed
  145. Zhang Z, et al. 2021. Oncoimmunology. 10:1912472. PubMed
  146. Han C, et al. 2021. Cell Reports. 34(6):108706. PubMed
  147. Lebratti T, et al. 2021. eLife. 10:00. PubMed
  148. Chew W, et al. 2016. Nat Methods. 13: 868-874. PubMed
  149. Oghumu S, et al. 2014. Immunology. 143: 109-119. PubMed
  150. Ellis G, et al. 2015. EMBO Rep. 16: 1203-1218. PubMed
  151. Sive J, et al. 2015. Leukemia. . PubMed
  152. Eddens T, et al. 2015. J Immunol. 195: 185 - 193. PubMed
  153. Haas R 2013. J Immunol. 190:3100. PubMed
  154. Zhou Z, et al. 2019. Oxid Med Cell Longev. 2019:1209307. PubMed
  155. An YA et al. 2017. eLife. 6 pii: e24071. PubMed
  156. Nowak WN, et al. 2019. Mediators Inflamm. 2019:1868170. PubMed
  157. Tran L, et al. 2017. Cancer Immunol Res. 5:1141. PubMed
  158. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  159. Zhang X, et al. 2022. Pharmaceutics. 14:. PubMed
  160. Higa T, et al. 2022. Nat Commun. 13:1500. PubMed
  161. Zhang Y, et al. 2020. Int J Mol Sci. 21:00. PubMed
  162. Szafran BN, et al. 2021. Chemical Research in Toxicology. 34(6):1556-1571. PubMed
  163. Dos Santos Dias L, et al. 2021. PLoS Pathog. e1009324:17. PubMed
  164. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  165. Cheng K, et al. 2021. Nat Commun. 12:2041. PubMed
  166. Syed A, et al. 2015. Infect Immun . 83: 3428-3437. PubMed
  167. Gabbita S, et al. 2015. PLoS One. 10: e0137305. PubMed
  168. Yang L, et al. 2020. Cell Stem Cell. 27(1):125-136. PubMed
  169. Sato H, et al. 2020. Cell Reports. 31(5):107579. PubMed
  170. McCreedy DA et al. 2018. eNeuro. 5(4) pii: ENEURO. PubMed
  171. Yoshida K, et al. 2022. Sci Rep. 12:17276. PubMed
  172. Donlan AN, et al. 2020. Anaerobe. 66:102275. PubMed
  173. Hug S, et al. 2021. Front Immunol. 12:642867. PubMed
  174. Xiao P, et al. 2021. JCI Insight. 6:. PubMed
  175. Yu X, et al. 2022. J Extracell Vesicles. 11:e12185. PubMed
  176. Dane EL, et al. 2022. Nat Mater. 21:710. PubMed
  177. Zhou Y, et al. 2022. Nat Commun. 13:2906. PubMed
  178. Kumari A, et al. 2022. Sci Rep. 12:15273. PubMed
  179. Li P, et al. 2021. Nat Immunol. 22:1107. PubMed
  180. Uher O, et al. 2021. Cancers (Basel). 13:. PubMed
  181. Callahan SM, et al. 2021. Curr Protoc. 1:e294. PubMed
  182. Scheiblich H, et al. 2021. J Immunol. 207:2143. PubMed
  183. Shcherbina A, et al. 2020. Cell Rep. 32:107964. PubMed
  184. Flommersfeld S, et al. 2021. Immunity. :. PubMed
  185. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  186. Honarpisheh P, et al. 2020. J Neuroinflammation. 0.9625. PubMed
  187. Chun E, et al. 2020. Immunity. 51(5):871-884.e6.. PubMed
  188. Di Genua C, et al. 2020. Cancer Cell. 37(5):690-704.e8.. PubMed
  189. Domingos-Pereira S, et al. 2019. Cancer Immunol Res. 7:621. PubMed
  190. Hiramoto T, et al. 2018. Mol Ther. 26:1255. PubMed
  191. Deng Z, et al. 2017. Oncogene. 36:639. PubMed
  192. Topper MJ et al. 2017. Cell. 171(6):1284-1300 . PubMed
  193. Yu VWC, et al. 2017. Cell. 168:944. PubMed
  194. Ayoub M, et al. 2019. Sci Rep. 9:6348. PubMed
  195. Perdomo J, et al. 2019. Nat Commun. 10:1322. PubMed
  196. Yu Y, et al. 2019. J Clin Invest. 129:546. PubMed
  197. Colliou N, et al. 2018. Gut Microbes. 9:279. PubMed
  198. Chen X et al. 2017. Cell stem cell. 21(6):747-760 . PubMed
  199. Hernández–Santos N, et al. 2018. Cell Host Microbe. 1.313194444. PubMed
  200. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  201. BÖiers C, et al. 2018. Dev Cell. 44:362. PubMed
  202. Kang SJ, et al. 2022. Food Sci Anim Resour. 42:903. PubMed
  203. Sodji QH, et al. 2022. Cancer Res Commun. 2:725. PubMed
  204. Li Z, et al. 2022. J Exp Clin Cancer Res. 41:74. PubMed
  205. Hu J, et al. 2022. Cell Mol Neurobiol. . PubMed
  206. Soto-Díaz K, et al. 2021. Front Immunol. 12:734349. PubMed
  207. Liu Y, et al. 2017. J Neurosci. 37(4):871-881. PubMed
  208. Li J, et al. 2020. Elife. 9:00. PubMed
  209. Wessel AW, et al. 2020. Nat Commun. 4.123611111. PubMed
  210. Callahan S, et al. 2020. Cell Microbiol. 22:e13210. PubMed
  211. Tang CC, et al. 2021. eLife. 10:00. PubMed
  212. Li Y, et al. 2020. Cell Stem Cell. 27(5):732-747.e7. PubMed
  213. Omori S, et al. 2021. Cell Reports. 34(6):108734. PubMed
  214. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  215. Morimura S, et al. 2021. Int J Mol Sci. :22. PubMed
  216. Socodato R, et al. 2020. Sci Signal. 13: . PubMed
  217. Miki Y, et al. 2016. J Biol Chem. 291: 15588 - 15601. PubMed
  218. Deng M, et al. 2020. Nat Commun. 11:2193. PubMed
  219. Xu H, et al. 2020. Immunity. 51(4):696-708.e9.. PubMed
  220. Peralta Ramos JM, et al. 2017. Front Immunol. 1.490277778. PubMed
  221. Timmons GA, et al. 2021. Front Immunol. 12:700431. PubMed
  222. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  223. Horn KJ, et al. 2022. Nat Commun. 13:3321. PubMed
  224. Lee SS, et al. 2022. Commun Biol. 5:654. PubMed
  225. Sá da Bandeira D, et al. 2022. Cell Rep. 40:111114. PubMed
  226. Grune J, et al. 2022. Nat Cardiovasc Res. 1:649. PubMed
  227. Pitsch J, et al. 2021. Ann Neurol. 89:666. PubMed
  228. Hu J, et al. 2022. J Neuroinflammation. 19:71. PubMed
  229. Mansell E, et al. 2020. Cell Stem Cell. . PubMed
  230. Hassan AO, et al. 2021. Cell Reports. 36(4):109452. PubMed
  231. Zee BM, et al. 2021. iScience. 24(6):102651. PubMed
  232. Nguyen PT, et al. 2020. Cell. 182(2):388-403.e15. PubMed
  233. Bayik D, et al. 2020. Cancer Discov. 1.256944444. PubMed
  234. Corrales L, et al. 2016. J Immunol. 196: 3191-3198. PubMed
  235. Koshida R, et al. 2015. Biochem Biophys Res Commun. 463: 109-115. PubMed
  236. Yu LC, et al. 2020. Front Neurol. 1.104166667. PubMed
  237. Frodermann V, et al. 2019. Nat Med. 25:1761. PubMed
  238. Qi S et al. 2016. eLife. 5 pii: e14756. PubMed
  239. Haloul M, et al. 2019. Sci Rep. 9:14050. PubMed
  240. Booth CAG, et al. 2018. Cancer Cell. 33:274. PubMed
  241. Xu X, et al. 2018. Cell. 175:1336. PubMed
  242. Habib S, et al. 2018. Infect Immun. 86:e00019. PubMed
  243. Ishidome T et al. 2017. EBioMedicine. 22:89-99 . PubMed
  244. Zhou Z, et al. 2022. Life (Basel). 12:. PubMed
  245. Zhao X, et al. 2022. Nat Protoc. 17:2240. PubMed
  246. Harnett MM, et al. 2022. Front Immunol. 13:953053. PubMed
  247. Yang Z, et al. 2021. Sci Adv. 7:. PubMed
  248. Shen X, et al. 2021. Front Immunol. 12:710750. PubMed
  249. Golden TN, et al. 2022. Front Pharmacol. 12:761496. PubMed
  250. Kren N, et al. 2020. Sci Rep. 10:7390. PubMed
  251. Viengkhou B, et al. 2021. J Neuroinflammation. 18:237. PubMed
  252. Nosho S, et al. 2020. Int J Mol Sci. 21:00. PubMed
  253. Runyan CE, et al. 2020. Aging Cell. 19:00. PubMed
  254. Burns JC, et al. 2020. eLife. 9:00. PubMed
  255. Tripathi H, et al. 2020. Stem Cell Rev Rep. 0.953472222. PubMed
  256. Guldner IH, et al. 2020. Cell. 183(5):1234-1248.e25. PubMed
  257. Ruan C, et al. 2020. Brain Behav Immun. 83:180. PubMed
  258. Lu P, et al. 2021. Nat Commun. 12:1042. PubMed
  259. Bugler-Lamb AR, et al. 2021. Mol Metab. 49:101197. PubMed
  260. Cuesta M, et al. 2016. J Immunol. 196: 2466 - 2475. PubMed
  261. Ma H, Wan S, Xia C 2016. J Leukoc Biol. 99: 1121 - 1129. PubMed
  262. Zhang H, et al. 2019. Mol Cell. 76:110. PubMed
  263. Sauma D, et al. 2017. Immunol Res. 10.1007/s12026-017-8936-9. PubMed
  264. Zhu Y, et al. 2021. EMBO J. 40:e105320. PubMed
  265. Yan W, et al. 2021. Front Med (Lausanne). 8:752223. PubMed
  266. Kim S, et al. 2021. Elife. 10:. PubMed
  267. Germundson DL, et al. 2022. Front Allergy. 3:870513. PubMed
  268. Tapia-Abellán A, et al. 2021. Sci Adv. 7:eabf4468. PubMed
  269. Ye X, et al. 2021. Cancer Biol Med. Online ahead of print. PubMed
  270. Cilenti F, et al. 2021. Immunity. . PubMed
  271. Maruoka M, et al. 2021. Molecular Cell. 81(7):1397-1410.e9. PubMed
  272. Lee J, et al. 2020. Cell Reports. 33(13):108560. PubMed
  273. Ni J, et al. 2020. Immunity. 52(6):1075-1087.e8. PubMed
  274. Dobson HE, et al. 2020. Mucosal Immunol. 0.901388889. PubMed
  275. Cho DS, et al. 2020. J Cachexia Sarcopenia Muscle. 1.396527778. PubMed
  276. Li X, et al. 2020. Nat Commun. 4.877777778. PubMed
  277. Liu Z, et al. 2020. Cell. 178(6):1509-1525.e19.. PubMed
  278. Yu X, et al. 2019. Nat Commun. 10:574. PubMed
  279. Xia P et al. 2018. Immunity. 48(4):688-701 . PubMed
  280. Nam GH, et al. 2018. Nat Commun. 9:2165. PubMed
  281. Milner MT, et al. 2022. STAR Protoc. 3:101295. PubMed
  282. Zelter T, et al. 2022. EMBO Rep. 23:e53641. PubMed
  283. Zhang X, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  284. Otvos B, et al. 2021. Clin Cancer Res. 27:2038. PubMed
  285. Zhang L, et al. 2021. iScience. 24(9):102942. PubMed
  286. Alam Z, et al. 2020. Cell Rep. 107825:31. PubMed
  287. Yang Y, et al. 2020. Cell Death Discov. 6:62. PubMed
  288. Li W, et al. 2021. Cell Transplant. 30:9636897211004090. PubMed
  289. Huang J, et al. 2014. J Immunol. 192:1972. PubMed
  290. Xiong X, et al. 2015. Stroke. 46: 2271-2276. PubMed
  291. Ford J, et al. 2019. Front Immunol. 2.502083333. PubMed
  292. Ge C, et al. 2020. Cell Reports. 29(13):4236-4244.e3.. PubMed
  293. Akk A, et al. 2019. Mol Immunol. 114:629. PubMed
  294. Sun J et al. 2018. Cell stem cell. 23(3):355-369 . PubMed
  295. Goldstein JM et al. 2019. Cell reports. 27(4):1254-1264 . PubMed
  296. Zeng Q, et al. 2022. iScience. 25:105151. PubMed
  297. Wüthrich M, et al. 2021. MBio. 12:e0201821. PubMed
  298. Vasudevan SO, et al. 2022. Cell Rep. 39:110755. PubMed
  299. Kohn EM, et al. 2022. J Immunol. 208:1417. PubMed
  300. Wolf SJ, et al. 2022. JCI Insight. 7:. PubMed
  301. Mohammadi MR, et al. 2021. Commun Biol. 4:685. PubMed
  302. Ha TC, et al. 2020. Hum Gene Ther. 32:458. PubMed
  303. Chen R, et al. 2021. Cell Reports. 34(7):108751. PubMed
  304. Lowe PP, et al. 2020. J Neuroinflammation. 0.913888889. PubMed
  305. León-Cabrera S, et al. 2014. Int J Biol Sci. 9 948 . PubMed
  306. Johansson J, et al. 2013. J Neurosci. 33:16016. PubMed
  307. Hohsfield LA, et al. 2020. J Neuroinflammation. 0.902083333. PubMed
  308. Horn LA, et al. 2017. Oncotarget. 8:57964. PubMed
  309. Tang Y, et al. 2019. Nat Commun. 10:4157. PubMed
  310. Metidji A et al. 2018. Immunity. 49(2):353-362 . PubMed
  311. Duarte D, et al. 2018. Cell Stem Cell. 22:64. PubMed
  312. Nenasheva T, et al. 2017. PLoS One. 12(6):e0178983. PubMed
  313. Howard ZM, et al. 2022. JCI Insight. 7:. PubMed
  314. Gavini CK, et al. 2022. J Neuroinflammation. 19:57. PubMed
  315. McCallion A, et al. 2022. Front Immunol. 13:961599. PubMed
  316. Wang S, et al. 2021. Commun Biol. 22:. PubMed
  317. Kumari P, et al. 2021. Cell Reports. 35(3):109012. PubMed
  318. Wilson ZS, et al. 2020. Sci Rep. 10:2142. PubMed
  319. Scheiblich H, et al. 2021. Cell. 184:5089. PubMed
  320. Gorina R, et al. 2014. J Immunol. 192:324. PubMed
  321. Liu Y, et al. 2015. BioMed Res Int. 2015 563425. PubMed
  322. Choi J, et al. 2015. PLoS One. 10: e0138592. PubMed
  323. Jaako P, et al. 2016. Leukemia. 10.1038/leu.2016.159. PubMed
  324. Di Genua C, et al. 2019. Haematologica. 104:2215. PubMed
  325. Uribe-Herranz M, et al. 2018. JCI Insight. 3. PubMed
  326. Vásquez M, et al. 2019. J Immunol. 203:696. PubMed
  327. Ohgomori T et al. 2019. J Comp Neurol. 528(1):14-31 . PubMed
  328. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  329. Yang YS, et al. 2022. Nat Commun. 13:6175. PubMed
  330. Deng Q, et al. 2021. Gut Microbes. 13:1. PubMed
  331. Kataru RP, et al. 2022. Front Aging. 3:864860. PubMed
  332. Woodring T, et al. 2022. iScience. 25:104934. PubMed
  333. Asadi Shahmirzadi A, et al. 2020. Cell Metabolism. 32(3):447-456.e6. PubMed
  334. Vaibhav K, et al. 2020. Sci Adv. 6:eaax8847. PubMed
  335. Prislovsky A, Strom T 2013. Exp Hematol. 41:789. PubMed
  336. Kajiwara C, et al. 2018. J Immunol. 200:623. PubMed
  337. Gomes T, et al. 2019. Front Immunol. 10:2088. PubMed
  338. Liu X, et al. 2021. Int J Med Sci. 18:3125. PubMed
  339. Friker LL, et al. 2020. Cell Rep. 30:3743. PubMed
  340. Chen F, et al. 2021. J Cell Mol Med. 25:11039. PubMed
  341. Howard ZM, et al. 2021. Am J Pathol. 191:730. PubMed
  342. Luciunaite A, et al. 2020. J Neurochem. 155:650. PubMed
  343. Pi J, et al. 2022. J Nanobiotechnology. 20:36. PubMed
  344. Zheng Y, et al. 2022. J Immunol. 208:501. PubMed
  345. van Geffen C, et al. 2021. Front Immunol. 12:695933. PubMed
  346. Milich LM, et al. 2021. J Exp Med. 218:. PubMed
  347. Messerer DAC, et al. 2020. Front Immunol. 11:571992. PubMed
  348. Markworth JF, et al. 2020. JCI Insight. 5:00. PubMed
  349. Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
  350. Chung S, et al. 2020. Am J Physiol Lung Cell Mol Physiol. L921:318. PubMed
  351. Ombrato L, et al. 2021. Nat Protoc. 16:872. PubMed
  352. Takeda K, et al. 2014. Am J Pathol. 184:686. PubMed
  353. Singhal P, et al. 2016. Proc Natl Acad Sci U S A. 113: 122 - 127. PubMed
  354. Cerina M, et al. 2017. Brain Behav Immun. 59:103-117. PubMed
  355. Haruwaka K, et al. 2019. Nat Commun. 4.455555556. PubMed
  356. Ireland L, et al. 2020. Front Immunol. 11:297. PubMed
  357. Steinkühler J, et al. 2018. J Cell Sci. 132. PubMed
  358. Kelley WJ, et al. 2022. JCI Insight. 7: . PubMed
  359. Smith KJ, et al. 2022. PLoS Biol. 20:e3001554. PubMed
  360. Jia Y, et al. 2022. Cell Discov. 8:21. PubMed
  361. Gao P, et al. 2021. Nat Commun. 1194:12. PubMed
  362. Ubags ND, et al. 2021. J Allergy Clin Immunol. 1049:147. PubMed
  363. Hara T, et al. 2021. Cancer Cell. 39(6):779-792.e11. PubMed
  364. Riedel SS, et al. 2021. Molecular Cell. 81(11):2332-2348.e9. PubMed
  365. Simoni L, et al. 2020. Cell Rep. 33:108330. PubMed
  366. Fukasawa K, et al. 2016. Sci Rep. 6:30918. PubMed
  367. Andresen L, et al. 2016. PLoS One. 11: 0148428. PubMed
  368. Pelly V, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.4. PubMed
  369. Jiang Y, et al. 2015. MBio. 6: e01426-15. PubMed
  370. Shi Y, et al. 2015. Mol Immunol. 66: 208-215. PubMed
  371. Tr änkner D, et al. 2019. Cell Rep. 29:791. PubMed
  372. Kunishita Y, et al. 2020. Front Immunol. 11:98. PubMed
  373. Säwen P et al. 2018. eLife. 7 pii: e41258. PubMed
  374. Nguyen HX et al. 2017. J Neurosci. 37(38):9269-9287 . PubMed
  375. Schroder WA, et al. 2019. Sci Rep. 9:12421. PubMed
  376. Wang C, et al. 2018. Sci Transl Med. 10. PubMed
  377. Nakamura K, et al. 2018. Cancer Cell. 33:634. PubMed
  378. Hao L, et al. 2021. Br J Pharmacol. 178:4726. PubMed
  379. Fan HH, et al. 2021. Methods Mol Biol. 2276:203. PubMed
  380. Chavez JS, et al. 2022. Cells. 11:. PubMed
  381. Shen L, et al. 2021. Cell Metabolism. 33(5):971-987.e6. PubMed
  382. Boguslawski KM, et al. 2020. Sci Adv. 6:eaax7515. PubMed
  383. Thurlow LR, et al. 2018. Cell Host Microbe. 24:261. PubMed
  384. Petriello MC, et al. 2018. Toxicol Sci. 162:548. PubMed
  385. Hilt ZT, et al. 2019. JCI Insight. 4:5. PubMed
  386. Ioanna E Galani et al. 2017. Immunity. 46(5):875-890 . PubMed
  387. Zhang B, et al. 2021. Nature. 599:471. PubMed
  388. Jones GS, et al. 2020. mSphere. 5:. PubMed
  389. Xiao M, et al. 2022. Mol Oncol. 16:1026. PubMed
  390. Awida Z, et al. 2021. Int J Mol Sci. 23:. PubMed
  391. Zha ZX, et al. 2022. Acta Pharmacol Sin. :. PubMed
  392. Zhang H, et al. 2022. Commun Biol. 5:916. PubMed
  393. Li J, et al. 2022. Nat Commun. 13:1481. PubMed
  394. Ren X, et al. 2021. Cell Death Dis. 12:484. PubMed
  395. Du Z, et al. 2020. J Allergy Clin Immunol. . PubMed
  396. Li X, et al. 2021. Cell Reports. 36(8):109607. PubMed
  397. Li J, et al. 2021. eLife. 10:00. PubMed
  398. Wan Y, et al. 2020. Cell Rep. 33:108346. PubMed
  399. Xiang W, et al. 2020. Signal Transduct Target Ther. 0.374305556. PubMed
  400. Xie Y, et al. 2020. Endocrinology. 161:00:00. PubMed
  401. Hohmann A, et al. 2016. Nat Chem Biol. 10.1038/nchembio.2115. PubMed
  402. Ramos-Sevillano E, et al. 2016. PLoS One. 12: 1005500. PubMed
  403. Kolan S, et al. 2015. PLoS One. 10: 0134113. PubMed
  404. Iwata-Yoshikawa N, et al. 2014. J Virol. 88:8597. PubMed
  405. Ma Y, et al. 2020. Front Immunol. 11:586685. PubMed
  406. Guenther C, et al. 2019. Front Immunol. 10:1138. PubMed
  407. Guarnerio J, et al. 2018. Nat Commun. 9:66. PubMed
  408. Li B, et al. 2019. Oncogenesis. 8:17. PubMed
  409. Omenetti S, et al. 2019. Immunity. 51:77. PubMed
  410. Yáñez A et al. 2017. Immunity. 47(5):890-902 . PubMed
  411. Han J, et al. 2022. Cell Discov. 8:122. PubMed
  412. Schmidts A, et al. 2020. J Immunother Cancer. 8:. PubMed
  413. Sethuraman SN, et al. 2020. Theranostics. 10:3397. PubMed
  414. Hohsfield LA, et al. 2021. Elife. 10:. PubMed
  415. Zhong J, et al. 2021. Commun Biol. 4:865. PubMed
  416. Zhang J, et al. 2021. Stem Cell Res Ther. 12:579. PubMed
  417. Chang MH, et al. 2021. Cell Rep. 37:109902. PubMed
RRID
AB_312794 (BioLegend Cat. No. 101211)
AB_312795 (BioLegend Cat. No. 101212)

Antigen Details

Structure
Integrin family, associates with integrin β2 (CD18), 170 kD
Distribution

Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subsets of T and B cells

Function
Adhesion, chemotaxis
Ligand/Receptor
ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen
Cell Type
B cells, Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653.

Gene ID
16409 View all products for this Gene ID 3684 View all products for this Gene ID
UniProt
View information about CD11b on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD11b Reagents Request Custom Conjugation
Description Clone Applications
PE/Cyanine7 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 750 anti-mouse/human CD11b M1/70 FC
TotalSeq™-A0014 anti-mouse/human CD11b M1/70 PG
Brilliant Violet 750™ anti-mouse/human CD11b M1/70 FC
TotalSeq™-B0014 anti-mouse/human CD11b M1/70 PG
TotalSeq™-C0014 anti-mouse/human CD11b M1/70 PG
Spark NIR™ 685 anti-mouse/human CD11b M1/70 FC
PE/Fire™ 640 anti-mouse/human CD11b M1/70 FC
APC anti-mouse/human CD11b M1/70 FC
Biotin anti-mouse/human CD11b M1/70 FC
FITC anti-mouse/human CD11b M1/70 FC
PE anti-mouse/human CD11b M1/70 FC,IHC
PE/Cyanine5 anti-mouse/human CD11b M1/70 FC
Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,IHC-F,ICC
Alexa Fluor® 488 anti-mouse/human CD11b M1/70 FC,IHC-F,3D IHC,SB
Alexa Fluor® 647 anti-mouse/human CD11b M1/70 FC,3D IHC,SB
Alexa Fluor® 700 anti-mouse/human CD11b M1/70 FC
Pacific Blue™ anti-mouse/human CD11b M1/70 FC
APC/Cyanine7 anti-mouse/human CD11b M1/70 FC
PerCP/Cyanine5.5 anti-mouse/human CD11b M1/70 FC
PerCP anti-mouse/human CD11b M1/70 FC
Brilliant Violet 421™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 570™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 605™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 650™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 711™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 785™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 510™ anti-mouse/human CD11b M1/70 FC,ICC
Ultra-LEAF™ Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,Block,Depletion,IHC-F,ICC
Purified anti-mouse/human CD11b (Maxpar® Ready) M1/70 FC,CyTOF®
Alexa Fluor® 594 anti-mouse/human CD11b M1/70 IHC-F,FC
PE/Dazzle™ 594 anti-mouse/human CD11b M1/70 FC
Spark YG™ 593 anti-mouse/human CD11b M1/70 FC
Spark YG™ 570 anti-mouse/human CD11b M1/70 IHC-F
PE/Fire™ 810 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 810 anti-mouse/human CD11b Antibody M1/70 FC
Spark Blue™ 550 anti-mouse/human CD11b M1/70 FC
Spark UV™ 387 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 806 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 780 anti-mouse/human CD11b M1/70 FC
Spark Blue™ 574 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
KIRAVIA Blue 520™ anti-mouse/human CD11b M1/70 FC
PE/Fire™ 744 anti-mouse/human CD11b M1/70 FC
Spark PLUS UV395™ anti-mouse/human CD11b M1/70 FC
Spark Red™ 718 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
Spark PLUS B550™ anti-mouse/human CD11b M1/70 FC
Spark YG™ 581 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
StarBright UltraViolet 575 anti-mouse/human CD11b M1/70 FC
StarBright UltraViolet 740 anti-mouse/human CD11b M1/70 FC
Spark PLUS V475™ anti-mouse/human CD11b M1/70 FC
Spark PLUS YG581™ anti-mouse/human CD11b M1/70 FC
Spark PLUS V450™ anti-mouse/human CD11b M1/70 FC
Go To Top Version: 1    Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account