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- Clone
- A23109A (See other available formats)
- Regulatory Status
- RUO
- Isotype
- Rat IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
C57BL/6 mouse splenocytes were stained with purified anti-mouse β2-microglobulin (clone A23109A) (filled histogram) or purified rat IgG2b, κ isotype control (open histogram), followed by goat anti-rat IgG PE.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 168702 | 100 µg | 151€ | ||||
β2-microglobulin (β2M) is a 12 kD, immunoglobulin-like, non-membrane-anchored glycoprotein. It non-covalently associates with the MHC class I heavy chain and certain class I-like molecules, functioning as the light chain. In complex with MHC class I, β2M is expressed on all leukocytes, platelets, endothelial cells, and epithelial cells. It plays a critical role in stabilizing MHC class I complexes for effective antigen presentation.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
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Clone A23109A can completely block the binding of clone A16041A on target cells.
Antigen Details
- Structure
- 12 kD, Ig like glycoprotein
- Distribution
-
Leukocytes, platelets, endothelial cells, epithelial cells
- Function
- Component of MHC class I complex
- Interaction
- MHC Class I molecules, Class I-like molecules
- Cell Type
- Endothelial cells, Epithelial cells, Leukocytes, Platelets
- Biology Area
- Adaptive Immunity, Immunology
- Molecular Family
- MHC Antigens
- Antigen References
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- Bernier GM, 1980. Vox Sang. 38:323.
- Williams DB, et al. 1989. J. Immunol. 142:2796.
- Gene ID
- 12010 View all products for this Gene ID
- UniProt
- View information about beta2-microglobulin on UniProt.org
Related FAQs
Other Formats
View All β2-microglobulin Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-mouse β2-microglobulin | A23109A | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-mouse β2-microglobulin
C57BL/6 mouse splenocytes were stained with purified anti-mo...
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