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ELISA MAX™ Deluxe Set Human AXL

Pricing & Availability
Regulatory Status
RUO
Other Names
AXL tyrosine-protein kinase receptor, ARK, AXL3, JTK11, Tyro7, UFO
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Product Citations
publications
ELISA-MAX_HumanAXLELISAKit_1_021326
  • ELISA-MAX_HumanAXLELISAKit_1_021326
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479204 5 plates 288€
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Description

Tyrosine-protein kinase receptor AXL (also known as Ark, Tyro7, and UFO), TYRO-3 (also known as Brt, Dtk, Rse, Sky, and Tif), and MERTK (also known as Eyk, Nym, and Tyro12) are included in the small family of TAM receptor tyrosine kinase. The TAM family is characterized by a combination of two immunoglobulin-like (Ig) domains and dual fibronectin type III (FNIII) repeat domains in the extracellular region, a transmembrane domain and a cytoplasmic tyrosine kinase domain.
One of the ligands of the TAM family, growth arrest specific gene 6 (Gas6), are secreted proteins and mediate their action through binding to and activating of AXL. AXL can also be activated by ligand-dependent dimerization, ligand-independent dimerization, and interaction between two monomers on neighboring cells and heteromeric dimerization with a non-TAM receptor.
AXL regulates multiple biological processes in cancer. Activated AXL, by binding to Gas6, promotes various downstream signaling pathways such as PI13k/Akt, JAK, and RAS/MEK/ERK pathways that can affect cancer cell proliferation, survival, migration, invasion, angiogenesis, stem cell maintenance, and immune suppression.

BioLegend’s ELISA MAX™ Deluxe Set Human AXL contains the components necessary for the accurate quantification of natural and recombinant human AXL. The set is designed for cost-effective and accurate quantification of human AXL in serum, plasma, cell culture supernatants, and cell lysates. BioLegend’s ELISA MAX™ Deluxe Sets Human AXL are sensitive, accurate, and robust.

Product Details
Technical data sheet

Kit Details

Kit Contents
  • Human AXL ELISA MAX™ Capture Antibody (200X)
  • Human AXL ELISA MAX™ Detection Antibody (200X)
  • Human AXL Lyophilized Standard
  • Avidin-HRP (1000X)
  • Substrate Solution F
  • Coating Buffer B (5X)
  • Assay Diluent B (5X)
Materials Not Included
  • Microwell plates: BioLegend Cat. No. 423501 is recommended
  • Wash Buffer: BioLegend Cat. No. 421601 is recommended, or PBS + 0.05% Tween-20 
  • Stop Solution: BioLegend Cat. No. 423001 is recommended, or acid solution, e.g. 2N H2SO4 
  • Plate Sealers: BioLegend Cat. No. 423601 is recommended 
  • PBS (Phosphate-Buffered Saline): 8.0 g NaCl, 1.16 g Na2HPO4, 0.2 g KH2PO4, 0.2 g KCl, add deionized water to 1 L; pH to 7.4, 0.2 μm filtered 
  • Deionized (DI) water 
  • A microplate reader capable of measuring absorbance at 450 nm 
  • Adjustable pipettes to measure volumes ranging from 2 μL to 1 mL 
  • Wash bottle or automated microplate washer 
  • Log-Log graph paper or software for data analysis 
  • Tubes to prepare standard dilutions 
  • Timer

 

Product Details

Verified Reactivity
Human
Application

ELISA
 
As a part of BioLegend's efforts to go green, each new lot of the ELISA MAX™ sets will include a summarized version of its manual. Click here for more information.
Sensitivity
54.705 pg/mL
Standard Range
133 – 8500 pg/mL

Antigen Details

Cell Type
B cells, Endothelial cells, Leukemia, Schwann Cells
Biology Area
Adaptive Immunity, Apoptosis/Tumor Suppressors/Cell Death, Cancer Biomarkers, Cell Proliferation and Viability, Immuno-Oncology, Immunology
Molecular Family
Innate Immune Signaling
Gene ID
558 View all products for this Gene ID
UniProt
View information about AXL on UniProt.org

Related FAQs

Do the ELISA MAX™ Deluxe Sets come with plates?

No, ELISA MAX™ Deluxe Sets do not come with plates. Coating Buffer and Assay Diluent (for blocking and dilutions) are included in these sets. Plates can be ordered separately (Cat No. 423501), and instructions for coating the plates are in the sets’ product manuals.

Go To Top Version: 1    Revision Date: 03.06.2026

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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