Loading...

PE/Cyanine7 anti-mouse F4/80 Antibody

Pricing & Availability
Clone
BM8 (See other available formats)
Regulatory Status
RUO
Other Names
EMR1, Ly71
Isotype
Rat IgG2a, κ
Ave. Rating
Submit a Review
Product Citations
publications
BM8_PECy7_122607
Thioglycolate-elicited BALB/c mouse peritoneal macrophages stained with BM8 PE/Cyanine7
  • BM8_PECy7_122607
    Thioglycolate-elicited BALB/c mouse peritoneal macrophages stained with BM8 PE/Cyanine7
Compare all formats See PE/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
123113 25 µg 84€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
123114 100 µg 243€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

F4/80, also known as EMR1 or Ly71, is a 160 kD glycoprotein of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80 has been widely used as a murine macrophage marker. It is expressed on a majority of tissue macrophages, including macrophages in the lung, gut, peritoneal cavity, thymus, and red pulp of the spleen, Kupffer cells, Langerhans cells, microglia, and certain dendritic cells. It is not expressed on macrophages located in the T cell areas of the spleen, lymph node, or Peyer's patch. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for the induction of CD8+ T cells-mediated peripheral tolerance.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Murine macrophages
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections1,2 and formalin-fixed paraffin-embedded sections6,7, Western blotting, and spatial biology (IBEX)12,13.

Application References
  1. Schaller E, et al. 2002. Mol. Cell. Biol. 22:8035. (IHC)
  2. Stevceva L, et al. 2001. BMC Clin Pathol. 1:3. (IHC)
  3. Kobayashi M, et al.2008. J. Leukoc. Biol. 83:1354. PubMed
  4. Poeckel D, et al. 2009. J. Biol Chem. 284:21077. PubMed
  5. Glass AM, et al. 2013. J. Immunol. 190:4830. PubMed
  6. Koehm S, et al. 2007. J. Allergy Clin. Immunol. 120:570. (IHC)
  7. Rankin AL, et al. 2010. J. Immunol. 184:1526. (IHC)
  8. Sasi SP, et al. 2014. J Biol Chem. 289:14178. PubMed
  9. Thakus VS, et al. 2014. Toxicol Lett. 230:322. PubMed
  10. Watson NB, et al. 2015. J Immunol. 194:2796. PubMed
  11. Hirakawa H, et al. 2015. PLoS One. 10:119360. PubMed
  12. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  13. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  2. Orberg E, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.53. PubMed
  3. Michela Miani et al. 2018. Cell metabolism. 28(4):557-572 . PubMed
  4. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  5. Sierro F, et al. 2017. Immunity. 47:374. PubMed
  6. Fan G, et al. 2021. Cell Death Dis. 12:73. PubMed
  7. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  8. Su Y, et al. 2022. J Hematol Oncol. 15:99. PubMed
  9. Taranto D, et al. 2021. Curr Protoc. 1:e147. PubMed
  10. Russler-Germain EV, et al. 2021. Immunity. 54:2547. PubMed
  11. Gerlach BD, et al. 2021. Cell Metab. 33:2445. PubMed
  12. Mills EL, et al. 2022. Cell Metab. 34:140. PubMed
  13. Gadipudi LL, et al. 2022. Clin Sci (Lond). 136:643. PubMed
  14. Van Deren DA, et al. 2022. Development. 149: . PubMed
  15. Liu K, et al. 2022. J Cell Biol. 221: . PubMed
  16. Yue Y, et al. 2022. Nat Biomed Eng. 6:898. PubMed
  17. Dolfi B, et al. 2022. Cell Rep. 39:110949. PubMed
  18. Silva Pereira S, et al. 2022. Elife. 11: . PubMed
  19. Akalu YT, et al. 2022. Elife. 11: . PubMed
  20. Liang Y, et al. 2022. Theranostics. 12:7729. PubMed
  21. Morrow RJ, et al. 2022. Cells. 11: . PubMed
  22. Cheng P, et al. 2023. Pharmacol Res. 188:106643. PubMed
  23. Niu J, et al. 2023. Nat Commun. 14:642. PubMed
  24. Chun J, et al. 2023. Cancers (Basel). 15: . PubMed
  25. Georgiev GI, et al. 2022. Cell Chem Biol. 29:811. PubMed
  26. Ajay AK, et al. 2022. Cell Rep. 38:110473. PubMed
  27. Chen K, et al. 2022. Adv Sci (Weinh). 9:e2104106. PubMed
  28. Gomez-Salinero JM, et al. 2022. Cell Stem Cell. 29:593. PubMed
  29. Friedman D, et al. 2022. J Immunol. 208:1845. PubMed
  30. Krasniewski LK, et al. 2022. Elife. 11:. PubMed
  31. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  32. Wu Z, et al. 2023. EMBO Rep. 24:e56524. PubMed
  33. Gu J, et al. 2023. J Cell Biochem. 124:557. PubMed
  34. Aso K, et al. 2023. Nat Commun. 14:984. PubMed
  35. Zhong WJ, et al. 2023. J Transl Med. 21:179. PubMed
  36. Cheng K, et al. 2023. Small. 19:e2300125. PubMed
  37. Dang YZ, et al. 2023. Neoplasma. 70:123. PubMed
  38. Seclì L, et al. 2023. J Immunother Cancer. 11:. PubMed
  39. Ji Y, et al. 2023. Nat Cell Biol. 25:726. PubMed
  40. Ishida K, et al. 2023. Front Immunol. 14:1111729. PubMed
  41. Brigo N, et al. 2023. Cells. 12:. PubMed
  42. Tsugawa H, et al. 2023. PLoS Pathog. 19:e1011139. PubMed
  43. Oh J, et al. 2023. Nat Commun. 14:3278. PubMed
  44. Poh AR, et al. 2017. Cancer Cell. 31:563. PubMed
  45. Fachi JL et al. 2019. Cell reports. 27(3):750-761 . PubMed
  46. Delvecchio FR, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:1543. PubMed
  47. Aggen DH, et al. 2020. Clin Cancer Res. . PubMed
  48. Cornax I, et al. 2021. Microorganisms. 9:00. PubMed
  49. Lauterbach MA, et al. 2020. Immunity. 51(6):997-1011.e7.. PubMed
  50. Schloss MJ, et al. 2022. Nat Immunol. 23:605. PubMed
  51. Li X, et al. 2022. Nat Commun. 13:2794. PubMed
  52. Dando SJ, et al. 2021. Invest Ophthalmol Vis Sci. 62:10. PubMed
  53. Tripathi H, et al. 2020. J Mol Cell Cardiol. 149:95. PubMed
  54. Yonemitsu K, et al. 2022. Sci Rep. 12:12007. PubMed
  55. Saxena A, et al. 2013. J Immunol. 191:4838. PubMed
  56. Giordano C, et al. 2014. Hum Mol Genet. . PubMed
  57. Sadek J, et al. 2021. EMBO Mol Med. 13:e13591. PubMed
  58. Frank AC, et al. 2021. Theranostics. 11:7570. PubMed
  59. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  60. Kesavan R, et al. 2021. Int J Mol Sci. 22:. PubMed
  61. Chou YJ, et al. 2020. Sci Rep. 10:8422. PubMed
  62. Sasse C, et al. 2022. Pathogens. 11:. PubMed
  63. Adachi Y, et al. 2022. Nat Commun. 13:5117. PubMed
  64. Weigert A, et al. 2022. Nat Commun. 13:6078. PubMed
  65. Allegrezza M, et al. 2016. Cancer Res . 76: 6253 - 6265. PubMed
  66. Coppo M, et al. 2016. Nat Commun. 7:12254. PubMed
  67. Shikatani EA et al. 2019. Cell Rep. 27(8):2304-2312 . PubMed
  68. Cheng G, et al. 2021. iScience. 24:102673. PubMed
  69. Shang W, et al. 2019. J Diabetes Res. 2019:5641271. PubMed
  70. Andreas N, et al. 2021. Arthritis Res Ther. 23:222. PubMed
  71. Huard A, et al. 2021. J Immunol. 206:1058. PubMed
  72. Achmus L, et al. 2020. Front Neurol. 11:577971. PubMed
  73. Nagatake T, et al. 2022. Mucosal Immunol. 15:289. PubMed
  74. Patnode M, et al. 2013. J Biol Chem. 288:26533. PubMed
  75. Han Y et al. 2019. Cell reports. 27(3):835-846 . PubMed
  76. Starkl P, et al. 2020. Immunity. 53(4):793-804.e9. PubMed
  77. Damal Villivalam S, et al. 2020. Nat Commun. 4313:11. PubMed
  78. Park JA, et al. 2021. J Hematol Oncol. 14:142. PubMed
  79. Currier MA, et al. 2017. Oncotarget. 8:17412. PubMed
  80. Sive J, et al. 2015. Leukemia. . PubMed
  81. Sharma S, et al. 2015. J Immunol. 194:5529. PubMed
  82. Koh EH, et al. 2018. Diabetes. 67(12). PubMed
  83. Luo W, et al. 2019. Mol Med Rep. 20:1007. PubMed
  84. Shimoda A, et al. 2017. Biochem Biophys Res Commun. 10.1016/j.bbrc.2017.07.126. PubMed
  85. Fujikura D, et al. 2013. PLoS One. 8:e55321. PubMed
  86. Hao F, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  87. Stutchfield B, et al. 2015. Gastroenterology. 149: 1896-1909.e14. PubMed
  88. Jondle C, et al. 2016. J Immunol. 196: 3088-3096. PubMed
  89. Maston LD, et al. 2017. Am J Physiol Lung Cell Mol Physiol. 312:L609. PubMed
  90. Zhang S, et al. 2019. Cell Metab. 29:443. PubMed
  91. Qu J, et al. 2018. J Immunol Res. 2018:7519856. PubMed
  92. Szafran BN, et al. 2021. Chemical Research in Toxicology. 34(6):1556-1571. PubMed
  93. Cheng K, et al. 2021. Nat Commun. 12:2041. PubMed
  94. Terashima Y, et al. 2020. Nat Commun. 11:609. PubMed
  95. Wu X, et al. 2021. Elife. 10:. PubMed
  96. Roy R, et al. 2022. Elife. 11:. PubMed
  97. Tay S, et al. 2014. J Immunol. 193:2087. PubMed
  98. Linde N, et al. 2018. Nat Commun. 9:21. PubMed
  99. Kornstädt L, et al. 2021. Front Immunol. 11:607048. PubMed
  100. Ajina R, et al. 2021. Cancer Immunol Res. 9:386. PubMed
  101. Smith AS, et al. 2022. J Immunother Cancer. 10:. PubMed
  102. Tomlinson KL, et al. 2021. Nat Commun. 12:1399. PubMed
  103. Wu MY, et al. 2021. Autophagy. 17:1096. PubMed
  104. Xiao Y, et al. 2022. Clin Transl Med. 12:e1071. PubMed
  105. Weber G, et al. 2014. J Exp Med. 211:1243. PubMed
  106. Francis M, et al. 2017. Toxicol Sci. 155(1):182-195. PubMed
  107. Wang ECE, et al. 2019. Cell Stem Cell. 24:654. PubMed
  108. Hulsmans M et al. 2017. Cell. 169(3):510-522 . PubMed
  109. Morimoto A, et al. 2021. Nat Commun. 12:2136. PubMed
  110. Zheng Z, et al. 2020. Cell Death Dis. 0.684722222. PubMed
  111. Lu X, et al. 2020. Sci Transl Med. 12:. PubMed
  112. Russler-Germain EV, et al. 2021. Elife. 10:. PubMed
  113. Ganguly K, et al. 2022. Front Immunol. 13:930449. PubMed
  114. Mojumdar K, et al. 2014. EMBO Mol Med. 6:1476. PubMed
  115. Xu X, et al. 2018. Cell. 175:1336. PubMed
  116. Oertel S, et al. 2017. Cell Mol Life Sci. 10.1007/s00018-017-2518-9. PubMed
  117. Reinfeld BI, et al. 2021. Nature. 593:282. PubMed
  118. Xu Z, et al. 2020. Cancer Immunol Res. 1354:8. PubMed
  119. Brigas HC, et al. 2021. Cell Reports. 36(9):109574. PubMed
  120. Volberding PJ, et al. 2021. Cell Reports. 35(8):109160. PubMed
  121. Torroella-Kouri M, et al. 2009. Cancer Res. 69:4800. PubMed
  122. Frodermann V, et al. 2019. Nat Med. 25:1761. PubMed
  123. Yong L, et al. 2022. Nat Commun. 13:4255. PubMed
  124. Golden TN, et al. 2022. Front Pharmacol. 12:761496. PubMed
  125. Garland KM, et al. 2021. Front Immunol. 12:753472. PubMed
  126. Zhao X, et al. 2022. Nat Protoc. 17:2240. PubMed
  127. Chiu Y, et al. 2014. J Immunol. 193:2207. PubMed
  128. Hamilton J, et al. 2015. J Immunol. 194:5022. PubMed
  129. Mangum L, et al. 2016. Toxicol Sci. 150: 169 - 177. PubMed
  130. Chung L et al. 2018. Cell host & microbe. 23(2):203-214 . PubMed
  131. Medler TR et al. 2018. Cancer cell. 34(4):561-578 . PubMed
  132. Xiong X et al. 2019. Mol Cell. 75(3):644-660 . PubMed
  133. Wanner-Seleznik GM, et al. 2020. Immunohorizons. 0.644444444. PubMed
  134. Tripathi H, et al. 2020. Stem Cell Rev Rep. 0.953472222. PubMed
  135. Engler AE, et al. 2020. Cell Reports. 33(13):108553. PubMed
  136. Deerhake ME, et al. 2021. Immunity. 54(3):484-498.e8. PubMed
  137. Lim CX, et al. 2020. Cell Rep. 3793:30. PubMed
  138. Alameh MG, et al. 2021. Immunity. 54:2877. PubMed
  139. Aktories P, et al. 2022. Cell Rep Methods. 2:100260. PubMed
  140. Maisel D, et al. 2016. PLoS One. 11: 0159716. PubMed
  141. Kim P, et al. 2015. Infect Immun . 83: 2992 - 3002. PubMed
  142. Ballet R, et al. 2014. PLoS Pathog. 10:1004550. PubMed
  143. Park HB, et al. 2020. Nat Microbiol. 1319:5. PubMed
  144. Li C, et al. 2021. Cell Metabolism. 33(8):1610-1623.e5. PubMed
  145. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  146. Ren Y, et al. 2020. Stem Cell Res Ther. 0.743055556. PubMed
  147. Alonso-Herranz L, et al. 2020. Elife. 9:00. PubMed
  148. Liu Z, et al. 2020. Cell. 178(6):1509-1525.e19.. PubMed
  149. Choi EW, et al. 2020. Sci Rep. 10:12001. PubMed
  150. Yamada KJ, et al. 2020. PLoS Pathog. 16:e1008354. PubMed
  151. Pathania AS, et al. 2022. Mol Ther Oncolytics. 25:308. PubMed
  152. Bachy S, et al. 2022. iScience. 25:103758. PubMed
  153. Anderson AE, et al. 2022. NPJ Regen Med. 7:6. PubMed
  154. Maulloo CD, et al. 2021. Front Immunol. 12:714842. PubMed
  155. Sun P, et al. 2022. Nat Commun. 13:6562. PubMed
  156. Efremova M, et al. 2018. Nat Commun. 9:32. PubMed
  157. Su W et al. 2019. Cancer Cell. 36(2):139-155 . PubMed
  158. Ahn D, et al. 2021. Cell Reports. 35(9):109196. PubMed
  159. Quenum Zangbede FO, et al. 2018. J Neurosci. 38:6737. PubMed
  160. Roy AG, et al. 2021. Int J Mol Sci. 22:. PubMed
  161. Zeng Q, et al. 2022. iScience. 25:105151. PubMed
  162. Tozuka M, et al. 2016. J Dermatol Sci. 82: 38-45. PubMed
  163. Nabet BY et al. 2017. Cell. 170(2):352-366 . PubMed
  164. Ponzetta A, et al. 2020. Cell. 178(2):346-360.e24.. PubMed
  165. Nagatake T, et al. 2018. J Allergy Clin Immunol. 142:470. PubMed
  166. Vasamsetti SB, et al. 2018. Immunity. 49:93. PubMed
  167. Chu LH, et al. 2018. Nat Commun. 9:996. PubMed
  168. Fujii T, et al. 2021. Bone Res. 9:4. PubMed
  169. Li J, et al. 2020. FASEB J. 34:3091. PubMed
  170. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  171. Heim CE, et al. 2020. Nature Microbiology. 5(10):1271-1284. PubMed
  172. Sharif O, et al. 2013. J Immunol. 190:5640. PubMed
  173. Song M, et al. 2013. Am J Pathol. 182:1308. PubMed
  174. Cai B, et al. 2020. Cell Metabolism. 31(2):406-421.e7.. PubMed
  175. Cheng HW, et al. 2022. Nat Commun. 13:2027. PubMed
  176. Stevenson ER, et al. 2022. J Pharmacol Exp Ther. 382:356. PubMed
  177. Baranwal G, et al. 2021. Physiol Rep. 9:e15094. PubMed
  178. Mendelsohn AC, et al. 2020. Am J Physiol Cell Physiol. 319:C997. PubMed
  179. Matsumura T, et al. 2022. Nat Commun. 13:7064. PubMed
  180. INAGAWA H, et al. 2016. In Vivo. 30: 205 - 211. PubMed
  181. Clemente C, et al. 2018. Nat Commun. 9:910. PubMed
  182. Laban H, et al. 2018. J Cell Biol. 217:1503. PubMed
  183. Li C, et al. 2018. Cell. 174:285. PubMed
  184. Nalbandian A, et al. 2017. Inflammation. 40:21:00. PubMed
  185. Wedekind MF, et al. 2021. iScience. 24(7):102759. PubMed
  186. Zhao Y, et al. 2020. Immunity. 51(6):1059-1073.e9.. PubMed
  187. Fletcher P, et al. 2021. J Toxicol Environ Health A. 84:152. PubMed
  188. Njock MS, et al. 2022. J Extracell Vesicles. 11:e12228. PubMed
  189. Chan M, et al. 2013. J Cell Sci. 126:3948. PubMed
  190. Muchenditsi A, et al. 2017. Am J Physiol Gastrointest Liver Physiol. 313:G39. PubMed
  191. Grayczyk JP et al. 2017. Cell host & microbe. 22(5):678-687 . PubMed
  192. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  193. Dallari S, et al. 2021. Cell Host Microbe. 29(6):1014-1029.e8. PubMed
  194. Yun H, et al. 2020. Immunity. 53(5):1050-1062.e5. PubMed
  195. Rao L, et al. 2020. Nat Commun. 11:4909. PubMed
  196. Bell CR, et al. 2022. Nat Commun. 13:2063. PubMed
  197. Zhu K, et al. 2022. EMBO Rep. 23:e54499. PubMed
  198. Montes de Oca M, et al. 2016. PLoS Pathog. 12: 1005398. PubMed
  199. Frank AC, et al. 2019. Nat Commun. 10:1135. PubMed
  200. Zhang C, et al. 2018. Cell Res. 28:323. PubMed
  201. Senatus L, et al. 2020. JCI Insight. 5:00. PubMed
  202. Urbanska AM, et al. 2020. Cancer Biother Radiopharm. 35:459. PubMed
  203. Yoshida H, et al. 2019. Cell. 176:897. PubMed
  204. Hoyer FF, et al. 2020. Immunity. 51(5):899-914.e7.. PubMed
  205. Zhang Z, et al. 2020. Nature. 579:415. PubMed
  206. Zhang L, et al. 2021. Front Mol Biosci. 8:647647. PubMed
  207. Martins R, et al. 2016. Nat Immunol. 17:1361-1372. PubMed
  208. Kwon H, Kim S 2016. Cell Death Dis. 7:22285. PubMed
  209. Kong P, et al. 2013. Am J Physiol Heart Circ Physiol. 305:1363. PubMed
  210. Gundra UM, et al. 2017. Nat Immunol. 1.195833333. PubMed
  211. Chavkin NW, et al. 2021. J Am Heart Assoc. 10:e019904. PubMed
  212. Bonavita E, et al. 2020. Immunity. 1215:53. PubMed
  213. Zhang L, et al. 2020. Cell. 442:181. PubMed
  214. Sangaletti S, et al. 2021. iScience. 24(6):102510. PubMed
  215. Sheng J, et al. 2021. eLife. 10:00. PubMed
  216. Fransén Pettersson N, et al. 2018. PLoS One. 13:e0203228. PubMed
  217. Fan HH, et al. 2021. Methods Mol Biol. 2276:203. PubMed
  218. Dye BR, et al. 2020. Biomaterials. 234:119757. PubMed
  219. Bajracharya B, et al. 2022. Biomed Res Int. 2022:9928362. PubMed
  220. Aguado B, et al. 2015. Sci Rep. 5: 17566. PubMed
  221. Li S, et al. 2017. Applied Materials & Interfaces. 10.1021/acsami.7b03160. PubMed
  222. Sadtler K, et al. 2017. Tissue Eng Part A. 23:1044. PubMed
  223. Petriello MC, et al. 2018. Toxicol Sci. 162:548. PubMed
  224. Hall JA, et al. 2020. Cell Metabolism. 32(4):665-675.e6. PubMed
  225. Liu Z, et al. 2020. STAR Protoc. 1:100029. PubMed
  226. Ramavath NN, et al. 2021. Front Immunol. 12:786680. PubMed
  227. Shue YT, et al. 2022. Nat Commun. 13:2690. PubMed
  228. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  229. Chng S, et al. 2016. Sci Rep. 6: 23820. PubMed
  230. Denis C, et al. 2014. Nucleic Acids Res. 42:7370. PubMed
  231. Riopel M, et al. 2019. Mol Metab. 20:89. PubMed
  232. Youssif C, et al. 2018. EMBO Mol Med. 10:e8403. PubMed
  233. Moriyasu T, et al. 2018. PLoS Negl Trop Dis. 12:e0006197. PubMed
  234. Nabekura T, et al. 2020. Immunity. 96:52. PubMed
  235. Bae S, et al. 2021. Cell Reports. 35(11):109264. PubMed
  236. Harvey RE et al. 2017. Endocrinology. 158(7):2179-2189 . PubMed
  237. Yu YR, et al. 2020. STAR Protocols. 11(3):e0150606. PubMed
  238. Tham SM, et al. 2021. Biomedicines. 9:. PubMed
  239. Pastor Arroyo EM, et al. 2022. Clin Sci (Lond). 136:557. PubMed
  240. Aggarwal N, et al. 2021. Cell Rep. 37:110170. PubMed
  241. Zhang L, et al. 2021. Mol Ther. 29:744. PubMed
RRID
AB_893490 (BioLegend Cat. No. 123113)
AB_893478 (BioLegend Cat. No. 123114)

Antigen Details

Structure
EGF-TM7 family member, 160 kD glycoprotein
Distribution

Majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen, Kupffer cells, Langerhans cells, bone marrow stromal cells, and a subset of dendritic cells

Function
Induction of immunological tolerance
Cell Type
Dendritic cells, Langerhans cells, Macrophages, Tregs
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Antigen References

1. Austy JM and Gordon S. 1981. Eur. J. Immunol. 11:805.
2. Hume DA, et al. 1983. J. Exp. Med. 158:1522.
3. Ruedl C, et al. 1996. Eur. J. Immunol. 26:1801.
4. McKnight AJ, et al. 1996. J. Biol. Chem. 271:486.
5. Lin HH, et al. 2005. J. Exp. Med. 201:1615.

Gene ID
13733 View all products for this Gene ID
UniProt
View information about F4/80 on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All F4/80 Reagents Request Custom Conjugation
Description Clone Applications
Purified anti-mouse F4/80 (Maxpar® Ready) BM8 FC,CyTOF®
PE/Dazzle™ 594 anti-mouse F4/80 BM8 FC
Brilliant Violet 650™ anti-mouse F4/80 BM8 FC
Brilliant Violet 711™ anti-mouse F4/80 BM8 FC
APC/Fire™ 750 anti-mouse F4/80 BM8 FC
TotalSeq™-A0114 anti-mouse F4/80 BM8 PG
TotalSeq™-B0114 anti-mouse F4/80 BM8 PG
TotalSeq™-C0114 anti-mouse F4/80 BM8 PG
Spark YG™ 570 anti-mouse F4/80 BM8 IHC-F
KIRAVIA Blue 520™ anti-mouse F4/80 BM8 FC
Ultra-LEAF™ Purified anti-mouse F4/80 BM8 FC,IHC,WB
Brilliant Violet 605™ anti-mouse F4/80 BM8 FC
Purified anti-mouse F4/80 BM8 FC,IHC,WB
Biotin anti-mouse F4/80 BM8 FC,IHC
FITC anti-mouse F4/80 BM8 FC
PE anti-mouse F4/80 BM8 FC
PE/Cyanine5 anti-mouse F4/80 BM8 FC
PE/Cyanine7 anti-mouse F4/80 BM8 FC
APC anti-mouse F4/80 BM8 FC
APC/Cyanine7 anti-mouse F4/80 BM8 FC
Alexa Fluor® 488 anti-mouse F4/80 BM8 FC,IHC-F,3D IHC
Alexa Fluor® 647 anti-mouse F4/80 BM8 FC,IHC-F,3D IHC
Pacific Blue™ anti-mouse F4/80 BM8 FC
PerCP anti-mouse F4/80 BM8 FC
PerCP/Cyanine5.5 anti-mouse F4/80 BM8 FC
Alexa Fluor® 700 anti-mouse F4/80 BM8 FC
Brilliant Violet 421™ anti-mouse F4/80 BM8 FC,IHC-F,SB
Brilliant Violet 510™ anti-mouse F4/80 BM8 FC
Alexa Fluor® 594 anti-mouse F4/80 BM8 IHC-F
Brilliant Violet 785™ anti-mouse F4/80 BM8 FC
APC/Fire™ 810 anti-mouse F4/80 BM8 FC
Spark NIR™ 685 anti-mouse F4/80 BM8 FC
Spark Blue™ 550 anti-mouse F4/80 BM8 FC
Brilliant Violet 570™ anti-mouse F4/80 BM8 FC
Brilliant Violet 750™ anti-mouse F4/80 BM8 FC
PE/Fire™ 810 anti-mouse F4/80 BM8 FC
Spark Red™ 718 anti-mouse F4/80 (Flexi-Fluor™) BM8 FC
Spark Blue™ 574 anti-mouse F4/80 (Flexi-Fluor™) BM8 FC
PE/Fire™ 640 anti-mouse F4/80 BM8 FC
PerCP/Fire™ 806 anti-mouse F4/80 BM8 FC
Go To Top Version: 2    Revision Date: 10/25/2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account